Dr. Siegel received her B.A. degree in English Literature from Brown University. She graduated A.O.A. from the University of Massachusetts Medical School, and received her Internal Medicine training at New York Presbyterian Hospital-Columbia University Medical Center. She completed fellowship training in hematology and oncology at the Dana Farber Cancer Center/MGH joint program and at New York Presbyterian Weil-Cornell Medical Center. Dr. Siegel cares for patients with gastrointestinal cancers, with an emphasis on hepatobiliary and colon cancers. She also conducts research in treatment outcomes, and teaches medical students and housestaff on the solid tumor service at Columbia. Dr. Siegel is involved in clinical and translational trials in hepatobiliary malignancies on many levels. She has developed many studies looking at new biologic agents for hepatobiliary cancers, and novel treatment strategies, such as liver transplantation, for cholangiocarcinomas. She is the Co-Chair of the hepatobiliary subcommittee of SWOG (an NCI-sponsored national trials network), and also serves on the NCI Hepatobiliary Task Force helping to develop a broad clinical trials portfolio nationally. She holds an NIH K23 award looking at novel methylation-related biomarkers in liver cancer, and recently received an NIH Team Leadership Award in recognition of her contributions to clinical trials in hepatobiliary oncology.