glossary

# A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

This cancer definition glossary is adapted from the National Cancer Institute online glossary.


Y

Y 90 ibritumomab tiuxetan (... ih-brih-TOO-moh-mab ty-oo-EKS-eh-tan)
A radiolabeled monoclonal antibody that is used to treat certain types of B-cell non-Hodgkin lymphoma and is being studied in the treatment of other types of B-cell tumors. It is made up of the monoclonal antibody ibritumomab plus the radioisotope yttrium Y 90. It binds to the protein called CD20, which is found on B cells. The radiation in the yttrium Y 90 may kill the cancer cells. Y 90 ibritumomab tiuxetan is a type of radiopharmaceutical. Also called yttrium Y 90 ibritumomab tiuxetan, Y 90 Zevalin, and IDEC-Y2B8.

Y 90 Zevalin (... ZEV-uh-lin)
A radiolabeled monoclonal antibody that is used to treat certain types of B-cell non-Hodgkin lymphoma and is being studied in the treatment of other types of B-cell tumors. It is made up of the monoclonal antibody ibritumomab plus the radioisotope yttrium Y 90. It binds to the protein called CD20, which is found on B cells. The radiation in the yttrium Y 90 may kill the cancer cells. Y 90 Zevalin is a type of radiopharmaceutical. Also called yttrium Y 90 ibritumomab , Y 90 ibritumomab tiuxetan, and IDEC-Y2B8.

yangona (yan-GOH-nuh)
An herb native to islands in the South Pacific. Substances taken from the root have been used in some cultures to relieve stress, anxiety, tension, sleeplessness, and problems of menopause. Yangona may increase the effect of alcohol and of certain drugs used to treat anxiety and depression. The U.S. Food and Drug Administration advises users that yangona may cause severe liver damage. The scientific name is Piper methysticum. Also called kava kava, intoxicating pepper, rauschpfeffer, and tonga.

yin and yang
In Chinese philosophy, yin and yang are opposite forces that form a whole. Everything contains both yin and yang in a balance that is always changing, such as hot and cold, day and night, and health and disease. In traditional Chinese medicine, disease is diagnosed and treated based on the balance of yin and yang.

YM598
A substance that is being studied as a treatment for advanced prostate cancer and for pain caused by prostate cancer that has spread to the bone. It belongs to the family of drugs called endothelin ETA receptor antagonists.

yoga (YOH-guh)
An ancient system of practices used to balance the mind and body through exercise, meditation (focusing thoughts), and control of breathing and emotions. Yoga is being studied as a way to relieve stress and treat sleep problems in cancer patients.

yohimbe (yo-HIM-bay)
A tree native to West Africa. The bark is used as a supplement for bodybuilding and to enhance male sexual performance. It contains the chemical yohimbine, which is being studied in the treatment of sexual dysfunction. Yohimbe may interact with certain drugs used to treat depression, high blood pressure, and high blood sugar. The scientific name is Pausinystalia yohimbe. Also called johimbe.

yttrium (IH-tree-um)
A rare elemental metal. A radioactive form of yttrium is used in radiation therapy and some types of immunotherapy.

yttrium Y 90 DOTA monoclonal antibody HuPAM4 (IH-tree-um...MAH-noh-KLOH-nul AN-tih-BAH-dee...)
A monoclonal antibody linked to a radioactive substance. It is being studied in the treatment of advanced pancreatic cancer. The monoclonal antibody called HuPAM4 is made in the laboratory and can locate and bind to pancreatic cancer cells. It is linked to a radioactive form of yttrium that can kill cancer cells without harming normal cells. Yttrium Y 90 DOTA monoclonal antibody HuPAM4 is a type of radioimmunoconjugate.

yttrium Y 90 DOTA-biotin (IH-tree-um ... BY-uh-tin)
A compound that contains the radioisotope yttrium Y 90 linked to the chemical biotin. Biotin is a molecule that binds strongly to the chemical streptavidin. Yttrium Y 90 DOTA-biotin will find tumor cells in the body that have been targeted by an antibody linked to streptavidin and kill them. It is being studied together with CC49-streptavidin in the treatment of cancer. Also called 90Y-DOTA-biotin.

yttrium Y 90 ibritumomab tiuxetan (IH-tree-um ... ih-brih-TOO-moh-mab ty-oo-EKS-eh-tan)
A radiolabeled monoclonal antibody that is used to treat certain types of B-cell non-Hodgkin lymphoma and is being studied in the treatment of other types of B-cell tumors. It is made up of the monoclonal antibody ibritumomab plus the radioisotope yttrium Y 90. It binds to the protein called CD20, which is found on B cells. The radiation in the yttrium Y 90 may kill the cancer cells. Yttrium Y 90 ibritumomab tiuxetan is a type of radiopharmaceutical. Also called Y 90 ibritumomab tiuxetan, Y 90 Zevalin, and IDEC-Y2B8.

yttrium Y 90 SMT 487
A substance that is being studied as a treatment for cancer. Also called yttrium Y 90-DOTA-tyr3-octreotide.

yttrium Y 90-DOTA-tyr3-octreotide (IH-tree-um ... OK-tree-oh-tide)
A substance being studied in the treatment of cancer. Also called yttrium Y 90 SMT 487.

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cholangiocarcinoma, or bile-duct (bile duct) cancer, arises from the tissues in the bile duct.