Dual Inhibition of PI3K-AKT-mTOR- and RAF-MEK-ERK-signaling is synergi

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  • August 27, 2014 at 5:21 pm #10480
    gavin
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    Dual Inhibition of PI3K-AKT-mTOR- and RAF-MEK-ERK-signaling is synergistic in cholangiocarcinoma and reverses acquired resistance to MEK-inhibitors.

    “Implications: AKT, mTOR and MEK are promising targets for a combinatorial treatment of cholangiocarcinoma cells even after acquisition of MEK inhibitor resistance.”

    http://www.ncbi.nlm.nih.gov/pubmed/25152244

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