Geographic Variation of Intrahepatic Cholangiocarcinoma, Extrahepatic

There are other issues as well, Duke.
1. current classification for CCA:
intrahepatic
hilar (peri-hilar)
Distal

2. The information is outdated.
This study includes intrahepatic CCA with primary liver cancer (HCC) therefore, we really don’t know the number of intrahepatic patients.
3. hilar and distal CCA are lumped together.
Although intrahepatic “used” to be lumped in with Hepatocellular Cancer ( it long has been changed. However; they followed the old classification.

Study eludes to the fact that intrahepatic CCA is similar to Hepatocellular cancer (well, it is not; they are two distinct, different cancers.) Therefore; if that were true (it is not) then incidence of occurrence would be similar to HCC.
Quote:
” It has been suggested that the etiology of ICC is more similar to that of another type of liver cancer, hepatocellular carcinoma (HCC), than to the etiology of ECC. If this is true, geographic incidence patterns and trends in ICC incidence should be more similar to that of HCC than ECC.”

Much work went into this study, but I am not sure of how much value it is to us.

Hugs,
Marion

Duke…correct, Mayo is in the process of recruiting additional participants for a more extensive data collection. The intent of their research to include international patients as well. A major problem is the tissue collection crossing international borders as well as the regulatory restrictions posed by the individual countries. This is pertaining to tissue only; blood samples can freely pass international borders.
Hugs,
Marion

I wonder if the data from the Mayo Clinic study supports this.

BTW, they won’t answer my emails about what they are doing and when they will report more findings. Major disappointment to me.

Duke