Phase II Trial of Dasatinib in Patients With Isocitrate Dehydrogenase

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  • August 6, 2016 at 12:19 am #87897
    bostonguy
    Spectator

    Has anybody here been involved with this trial? I think dasatinib will be the next thing we try for my mother if AG-120 stops working, so I am interested to hear from people who have experience being in this trial. My mother has the IDH-1 mutation, but also has an ABL1 rearrangement (not BCR/ABL, but at the same location), so this gives even more reason to believe dasatinib would be effective.

    May 17, 2015 at 5:56 pm #87896
    gavin
    Moderator

    You’re most welcome Charlotte and thanks for the link you gave about this trial. Hopefully it will be of use to others as well.

    Thank you,

    Gavin

    May 17, 2015 at 12:04 pm #87895
    charlotteb
    Spectator

    Thank you for sharing Gavin!
    I found an article about this new trial, I think this trial could be very interesting for patients carrying the IDH mutation.
    https://giving.massgeneral.org/target-cancer-research/

    April 30, 2015 at 5:41 pm #11187
    gavin
    Moderator

    Phase II Trial of Dasatinib in Patients With Isocitrate Dehydrogenase (IDH)-Mutant Advanced Intrahepatic Cholangiocarcinoma

    https://clinicaltrials.gov/ct2/show/NCT02428855

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