Check out the delcath website. In very simplistic terms, as I understand it: it is almost like dialysis in that the doctors would perform an infusion, but instead of letting the chemo out into the blood stream, it is directed from the liver to an external filter and then place back into the blood stream uncontaminated.
The woman I spoke to at the Natl Cancer Institute advised that it is a bit of a strenuous process for the patient and requires a 4 day hospital stay. The NCI location is (I think) the only trial for primary liver cancer. The others are for melanoma, but please verify that with them as things may have changed.
It looks extraordinarily promising.