Has anyone researched SAHA?

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  • August 25, 2006 at 12:16 pm #14569
    peter
    Member

    Thank you Caroline. Please keep us posted on AZD2171 as well. I now must consider what protocols I may try and am trying to gather as much information as possilbe.

    -Peter

    August 25, 2006 at 6:19 am #14568
    caroline-stoufer
    Spectator

    I am looking into clinical trials for AZD2171, the new generation of Avastin.

    I have a cousin who is a rep for AstraZeneca, the manufacturer of the drug, and I asked her what she could find out.

    I will let you know what I find out.

    -Caroline

    August 22, 2006 at 2:07 pm #213
    peter
    Member

    SAHA was invented by Columbia Chemistry professor Ronald Breslow and is a synthetic compound which targets tumor cells forcing the juvenile tumor cells to mature into stable cells and stop dividing.
    MD Anderson lists some Phase I trials, most seem aimed at leukemia, with one where SAHA is used in conjunction with Gemcitabine targeting ‘solid tumors’.

    http://utm-ext01a.mdacc.tmc.edu/dept/prot/clinicaltrialswp.nsf/index/2005-0140

    Has anyone researched SAHA or know any more about it?

    -Peter

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