Hi,
As always,consult your oncologist BEFORE any change of your treatment plan.
Thanks to the CC foundation ,according to the package insert I picked up at the Genentech booth for Xeloda(dated 4/2011).
If you are on montherapy only with xeloda; the adverse effect of nail DISORDER is about 7% in a phase II trail involved 162 patients of stage IV breast cancer.
If you are on a combination therapy with Xeloda,the chance is about 14%,and 2% of them is in the Grade 3 category.(the scale is from Grade1-Grade 4 ,a scale developed to measure the adverse drug reaction of medication;Grade 4 is being the most serious.):the chance for nail DISCOLORATION is 6% .
Generally,dose reduction of Xeloda may be needed base on the condition of the nails and other related issues until problem resolved ; this is why you should call your oncologist and make an appointment to let him/her to determine what is the best way to due with the problem.You should not change any current treatment plans until you talk to the oncologist.
There is also a phone # (1-877-987-2487) you can call for support and a oncology nurse who trained about Xeloda will answer your questions about Xeloda 24/7 in 150 languages;it is provided by Genentech,the company that makes Xeloda.
God bless.