Understanding Chemotherapy

My mom was diagnosed with Cholangiocarcinoma with mets to her liver 12/13 and began treatment 1/13. She has had one round of sphere radiation to her liver at UNC and was rescanned 4/13 and saw that her large tumors in her liver were shrinking but her small tumors were growing. Weird b/c she has been receiving treatment for Cholangiocarcinoma with Cisplatin and Gemcitabine. She began a research trial through Johns Hopkins with a company called Cellpath Therapeutics in which they took a sample of her blood and tested her cancer cells against several different chemo drugs. Her results came back and it looks like Irinotecan was the most sensitive (effective) as well as Pemetrexed. It is a little confusing because Irinotecan is used primarily for colorectal cancer and Pemetrexed is used for Lung Ca. Have you all had any experience with the usage of these meds for the treatment of cholangiocarcinoma or liver ca? Thanks

Allison Pearce