Search Results for 'gemcitabine cisplatin'
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Search Results
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Phase II study of copanlisib (BAY 80-6946) in combination with gemcitabine and cisplatin in advanced cholangiocarcinoma
Gavin
A Randomized, Controlled Study to Compare the Efficacy, Safety and Pharmacokinetics of Melphalan/HDS Treatment Given with Cisplatin/Gemcitabine versus Cisplatin/Gemcitabine (Standard of Care) alone in Patients with Intrahepatic Cholangiocarcinoma
https://clinicaltrials.gov/ct2/show/NCT03086993
Gavin
A Randomized Phase II Study of Nivolumab in Combination with Gemcitabine/Cisplatin or Ipilimumab as First Line Therapy for Patients with Advanced Unresectable Biliary Tract Cancer
https://clinicaltrials.gov/ct2/show/NCT03101566
Gavin
A Randomized, Controlled Study to Compare the Efficacy, Safety and Pharmacokinetics of Melphalan/HDS Treatment Given with Cisplatin/Gemcitabine versus Cisplatin/Gemcitabine (Standard of Care) alone in Patients with Intrahepatic Cholangiocarcinoma
https://clinicaltrials.gov/ct2/show/NCT03086993
Gavin
Hello everyone,
Happy New Year. We pray for that! I haven’t posted since my original intro or two. Here is our experience over the last 9 months. We would appreciate any feedback, encouragement or suggestions from your experience.
My husband was diagnosed last Spring with extrahepatic cholangiocarcinoma. It was operable but he did not have negative margins, but displasya and Ca in Situ remaining after his CBD resection.
He did have one node positive of 6 and they had said his cancer was stage IIA.
After the surgery, he had chemotherapy with Gemcitabine and Cisplatin for 9 weeks with 2 weeks on, 1 week off, 3 times.
He was very lucky and had no side effects that altered lifestyle or work. In July, he had a few week break and then went into radiation and chemo with capecitabine. Went thru this well. Got beat up towards end of radiation. No prob with capecitabine. Then there was a few week break and we went back to start the Gemcitabine and Cisplatin over 9 weeks just like the beginning. He had one treatment and his platelets dropped and did not rebound for 2nd treatment. Oncologist suggested taking a few weeks off to continue to recover from radiation. Went back to start chemo again, and same thing happened. One treatment and platelets did not recover enough. So another 2 week break to “heal” and started Oral Capecitabine. Did ok, 14 days on. 3 days after his 1st round of Capecitabine, he got really sick. Think it was colitis or some other bacteria. We had a terrible two weeks during Christmas. Vomiting and diarrhea so severe that I had to take him to infusion for fluids and potassium about every 2nd or 3rd day for 2 weeks.
We are rebuilding him now and will meet with oncologist next week to discuss options for further chemo.
The biggest concern we are facing is that his Ca 19 9 had not decreased since the original surgery. It slowly went up but stayed under 100. In November it crept up to 140, then 280, then 330. 12/20 it was 780 and this past friday was at 2098. We are so scared. He is gaining weight back and eating alot to be ready for chemo. We have scans next week but he had a chest ct last week, unrelated and it was clear. Upper abdomen was picked up and that was clear. So, they will do abdomen and pelvic ct and we will go from there. Last Pet scan was October and nothing showed.
We arent certain what chemo will be next. We are hoping he can get back on the Gem/Cis. Any feedback is appreciated.
Best wishes to everyone
Patti
A Phase 3, First Line Study of Pemigatinib vs Gemcitabine/Cisplatin in Patients with Cholangiocarcinoma
https://clinicaltrials.gov/ct2/show/NCT03656536
Gavin
Durvalumab or Placebo in Combination With Gemcitabine/Cisplatin in Patients With 1st Line Advanced Biliary Tract Cancer (TOPAZ-1) (TOPAZ-1)
https://clinicaltrials.gov/ct2/show/NCT03875235
Gavin
Phase II study of copanlisib (BAY 80-6946) in combination with gemcitabine and cisplatin in advanced cholangiocarcinoma
Durvalumab or Placebo in Combination With Gemcitabine/Cisplatin in Patients With 1st Line Advanced Biliary Tract Cancer (TOPAZ-1) (TOPAZ-1)
https://clinicaltrials.gov/ct2/show/NCT03875235
Gavin
A Phase 3, First Line Study of Pemigatinib vs Gemcitabine/Cisplatin in Patients with Cholangiocarcinoma
https://clinicaltrials.gov/ct2/show/NCT03656536
Gavin
A Randomized Phase II Study of Nivolumab in Combination with Gemcitabine/Cisplatin or Ipilimumab as First Line Therapy for Patients with Advanced Unresectable Biliary Tract Cancer
Durvalumab or Placebo in Combination With Gemcitabine/Cisplatin in Patients With 1st Line Advanced Biliary Tract Cancer (TOPAZ-1) (TOPAZ-1)
https://clinicaltrials.gov/ct2/show/NCT03875235
Gavin
A Randomized Phase II Study of Nivolumab in Combination with Gemcitabine/Cisplatin or Ipilimumab as First Line Therapy for Patients with Advanced Unresectable Biliary Tract Cancer
https://clinicaltrials.gov/ct2/show/NCT03101566
Gavin
Durvalumab or Placebo in Combination With Gemcitabine/Cisplatin in Patients With 1st Line Advanced Biliary Tract Cancer (TOPAZ-1) (TOPAZ-1)
Phase II study of copanlisib (BAY 80-6946) in combination with gemcitabine and cisplatin in advanced cholangiocarcinoma
