Blocking of POLQ Gene could boost effectiveness of Radiotherapy
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“The scientists discovered that blocking the activity of a gene called POLQ – which is switched on in cancer cells – increased the ability of radiotherapy to destroy tumours.
This means the development of drugs to block POLQ would potentially increase the effectiveness of radiotherapy without increasing the side effects of the treatment.
One of the lead authors Dr Geoff Higgins, a Cancer Research UK scientist at the Gray Institute, said: “We’ve sieved through a vast pool of promising genetic information and identified a gene that could potentially be targeted by drugs to improve the effectiveness of radiotherapy.”
Gavin
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