Brittle Nails
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Thanks for your advice. I should have mentioned that I finished the xeloda in Feb this year. I go for blood work on Tuesday. I wonder if the brittle nails are related to low protein. Thanks again, Johanna
Hi,
As always,consult your oncologist BEFORE any change of your treatment plan.
Thanks to the CC foundation ,according to the package insert I picked up at the Genentech booth for Xeloda(dated 4/2011).
If you are on montherapy only with xeloda; the adverse effect of nail DISORDER is about 7% in a phase II trail involved 162 patients of stage IV breast cancer.
If you are on a combination therapy with Xeloda,the chance is about 14%,and 2% of them is in the Grade 3 category.(the scale is from Grade1-Grade 4 ,a scale developed to measure the adverse drug reaction of medication;Grade 4 is being the most serious.):the chance for nail DISCOLORATION is 6% .
Generally,dose reduction of Xeloda may be needed base on the condition of the nails and other related issues until problem resolved ; this is why you should call your oncologist and make an appointment to let him/her to determine what is the best way to due with the problem.You should not change any current treatment plans until you talk to the oncologist.
There is also a phone # (1-877-987-2487) you can call for support and a oncology nurse who trained about Xeloda will answer your questions about Xeloda 24/7 in 150 languages;it is provided by Genentech,the company that makes Xeloda.
God bless.
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