Cardiotoxicity (chest Pain) of Xeloda (Capecitabine) – Diltiazem TX

Hi, Marion,
Yes, the linked study is for 5 patients, but the side effect of 5FU are listed long time ago , this article got my attention because of they specifically mention the word “capecitabine induced”.
Below is another link about 5FU cardiotoxicity.

http://7thspace.com/headlines/428372/5_fu_induced_cardiac_toxicity___an_underestimated_problem_in_radiooncology.html

I do not think most of the CCA patient will see a cardiologist until their GP or oncologist suggesting the patients to do so. I think getting a EKG reading for 24 hours( using holter monitor device ) every year is a good starting point.but it needs an order from your GP or cardiologist. Standard EKG at the doctor or at the hospital may not pick up the EKG change at the time of testing.
God bless.

Hi,
Cardio toxicity of 5FU include angina,arrhythmias including,Ventricular tachycardia,cardiogenic shock,chest pain(unspecified),coronary vassos plasm,myocardial infarction,palpitations,electrocardiographic changes and sudden death.
Patient who have cardiac problems should mention it to the doctor before starting 5FU or capecitabine. And adequate hydration is helpful.

Beta-blockers such as Lopressor; calcium channel blockers such as Diltiazem and nitrates such as nitroglycerin tablet or the patch will help to relieve the chest pain.
Upon such findings, as a patient on Xeloda for almost a year, once again, I will tap into my resources to see what they can suggest to me.
God bless.