Cediranib or placebo in combination with cisplatin and gemcitabine ch

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  • August 20, 2015 at 3:13 am #89474
    marions
    Moderator

    Cedrianib (AZD2171) is a Vascular endothelial growth factor receptor (VEGFR) 1, 2, and 3 tyrosine kinase inhibitor [VEGFR-1 (FLT-1)|VEGFR-2 (FLK-1/KDR|VEGFR-3 (FLT-4)] inhibitor.
    The study reported more adverse events for patients receiving the inhibitor than those patients treated with Gemcitabine and Cisplatin. Most importantly it did not improve Progression Free Survival.

    August 19, 2015 at 9:23 pm #11623
    gavin
    Moderator

    Cediranib or placebo in combination with cisplatin and gemcitabine chemotherapy for patients with advanced biliary tract cancer (ABC-03): a randomised phase 2 trial.

    http://www.ncbi.nlm.nih.gov/pubmed/26179201

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