Chemo Agents and Solid Tumor Biomarkers-From Caris Life Sciences

Hi, everyone,

Link= Agents Biomarker Platform
cisplatin, carboplatin ERCC1 RT-PCR
BRCA1 RT-PCR
docetaxel, paclitaxel TLE3 IHC
capecitabine, fluorouracil, pemetrexed TS (TYMS) RT-PCR
doxorubicin, liposomal-doxorubicin, epirubicin TOP2A RT-PCR
Pgp RT-PCR
irinotecan, topotecan TOPO1 RT-PCR
gemcitabine RRM1 RT-PCR
erlotinib, gefitinib EGFR RT-PCR
cMET IHC, FISH
temozolomide, dacarbazine MGMT IHC
nab-paclitaxel SPARCm, SPARCp IHC
abiraterone, bicalutamide, flutamide AR IHC
fulvestrant, tamoxifen, toremifene; anastrozole, exemestane, letrozole; megestrol acetate; leuprolide, goserelin ER IHC
PR IHC
everolimus, temsirolimus PIK3CA Sequencing
PTEN IHC
trastuzumab, lapatinib HER2 IHC, FISH/CISH
imatinib, sunitinib cKIT (GIST only) Sequencing
clinical trials (MEK inhibitors; BRAF inhibitors) BRAF Sequencing
clinical trials (MEK inhibitors; BRAF inhibitors) KRAS Sequencing
clinical trials (MEK inhibitors; BRAF inhibitors) NRAS(Thyroid) Sequencing

God bless.