Chemo Embolization VS. Y-90 Radio Embolization
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Hi,
Good choice based on what I have just researched.
Sorry I take so long to unswer your question. I feel more comfortable this way.
Be sure to keep in touch,so everybody can be of benefit from your mom’s case.
God bless.Hi,
After I read your previous entries, and based on what my experience of it(no side effects,may be subtle pain ;your mom may be a bit different since she had 30 or so little lesions plus a 5cm one).I will go along with JH recommendation.
23hr hospital observation may be required or she can go home the same day depends on JH protocol.
Chemoembro with cisplatin,mitomycin and Adriamycin alone or in combination mix with an oily vehicle or beads to inject into the liver via the groin under CAT SCAN direction angiogram. RFA may be use later to kill the tumor off or the chemoembro can be repeated to get the maximum effects out of it a month later.Radition with Yttrium 90(SIR-Spheres)using beads of 32 microns in size to carry the Yttrium 90,injected into the hepatic artery using CAT SCAN as a guide.
the beads lodge in the vasculature of the tumors;The beta radiation remains localized,penetrating a mean of 2.4mm in tissue and destroy the tumor cells.Half life of the radiation=2.7days and most of them(>97% )is delivered in weeks,with almost no radiation remaining after 1 month.-company info.by Sir-Spheres.provided at the ASCO 6/2011 convention at Chicago.“The ideal patient to use this method would have the following:(-From SIR-Spheres company booklet 268-M-Leaf REV.1 0910)
1. Liver-only or liver-predominant disease.
2. Good performance status.
3. Adequate Liver function
4. Remaining Chemotherapy options.
and this radiation procedure has no therapeutic effect on EXTRA hepatic disease.”As far as I can understand at this moment, most of the time this radiation procedure is used in combination with chemo to achieve or prolong “time to progression” of chemo alone treatments or in chemotherapy refractory patients.
Keep in touch so we can also help others.
God bless;.Hi PCL 1029,
They said that they’d target the left side of the liver first, since that’s where 90-95% of the tumors are. He said that hers is ICC and that it most likely originated in a smaller “branch” of her bile duct inside the liver (but not in the center where the “branches” are larger (if that analogy makes sense). It has not spread to the gallbladder. Let me know if you need any other info! For now, I guess we’ll probably try the chemo embolization first and if that doesn’t work, go to radio embolization next.
Thanks,
KateHi All-
We went to Johns Hopkins for my mom, and were told (as we suspected) that her ICC is unresectable due to spread to the right side of the liver. They recommended chemo embolization, but the one doctor also said that radio embolization is also an option. He said there has not been as much research done on Radio Embolization as chemo, so we are scheduled to have Chemo Emb on Weds.However, I just spoke with Dr. Kato’s PA, and she said that radio embolization may be a better place to start. Does anyone have any experience of one working better than the other? They’re not sure if surgery will ever be an option, but I am keeping hope that it one day will be if the tumors shrink or die on the right side. Any insight you can provide would be helpful–thanks!
(Just as background, she has >30 tumors on her liver…majority on the left side with a few on the right side. She is 57 years old and otherwise very healthy. She also has no symptoms or pain yet up to this point.)
~Katie
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