Differences in immunohistochemical biomarkers between intra- and extra

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  • May 4, 2014 at 6:41 am #82120
    lainy
    Spectator

    Thanks Marion. I know nothing can be changed and I accept that, just wondered. I fell asleep at 9PM tonight and awoke at 1130PM and now I am wide awake!!!

    May 4, 2014 at 5:56 am #82119
    marions
    Moderator

    Lainy…..I can’t answer that question, but I do know that Teddy had made an informed decision. Would things be different now? I suppose that many of us think that way, but I have come to the conclusion that nothing can change the outcome for what it was.
    Hugs,
    Marion

    May 3, 2014 at 6:37 pm #82118
    lainy
    Spectator

    Thanks Marion and Gavin. Teddy had Distal CC and it was at the Ampulla of Vater and Duodenum. Also the 2 times it came back it came back to that place.
    I have always wondered why 4 DOCs said no to chemo from the very beginning because “of the type of CC he had”. They said it would not work. This is the only thing I have always thought about. Any ideas on this? Of course this was 8 years ago. It’s like the one closure I never had.

    May 3, 2014 at 6:18 pm #82117
    marions
    Moderator

    Thanks, Gavin. CCA differs molecularly the three subgroups: Intrahepatic, Distal and Perihilar(Klatskin) This explains the varied drug response to drugs currently used for our patients and the role of molecular profiling.

    May 3, 2014 at 5:41 pm #9919
    gavin
    Moderator

    Differences in immunohistochemical biomarkers between intra- and extrahepatic cholangiocarcinoma: A Systematic Review and Meta-analysis.

    http://www.ncbi.nlm.nih.gov/pubmed/24787096

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