Gemzar infused too fast
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Hi,
The reason for giving Gemzar not longer than 30 min. is the concern of the increase toxicity if given longer than 30min.Longer infusion rate(ie:>70min.) resulted in 2-fold increase of peak Gemzar cell concentration than the same dose given over 30 min.
The half-life (the time that half of the dose is eliminated from the body)of Gemzar is affected by the duration of infusion,age(older patient takes longer to get rid of the drug),and gender(men are almost 1/3 faster in elimination of the drug than women) due to the changes in the volume of distribution and clearance. Up to 98% of the Gemzar is excreted through the kidney.—- from http://www.clinical pharmacology 2012.
God bless.I’m getting 1700 of Gemzar, takes 30 minutes… I weigh about 195, 5’10”. I’ve only had about 4-5 minutes of very slight burning in the vein during infusion, but nothing other than that and it was about 4 weeks ago. 10 minutes sounds very quick but as Percy said, unless it was a very low dose you would think that it may have made you nauseous with such a quick infusion. The nurses all say you can’t take more than 30 minutes (toxic or something after that) but haven’t heard anything about too fast a rate…
Its a little bag. Not sure how much.
Its not hooked up on the pump, is just a slow flow they set. But for some reason, the nurse raised my IV poll as high as it would go….I will be talking to my doctor about it at the next visit.Hi,
I will ask them,the nurses why.and talk to the doctor personally on the next appointment for the reason. I will be surprised if you did not get sick ;it is too fast unless your dose is very low. what is the dose on the chemo bag for Gemar? less than 1000mg?
God bless.
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