Has immuno-theraphy been tried intrahepatic cholangiocarcinoma (ICC)?

Discussion Board Forums Introductions! Has immuno-theraphy been tried intrahepatic cholangiocarcinoma (ICC)?

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  • #94657
    marions
    Moderator

    Julian….welcome to our site. I am sorry to hear of your sister in-laws diagnosis.
    I hope for others to come forward and share their experience regarding FGFR fusion as well as immunotherapy trials.
    In the meantime you may want to take a look at our extensive clinical trials site.
    http://www.cholangiocarcinoma.org/punbb/viewforum.php?id=14

    I am aware of the International Clinical Trials Registry Platform
    http://www.who.int/ictrp/search/en/

    which lists the Chinese – Chinese Clinical Trial Registry (ChiCTR)

    I hope this helped a bit, dear Julian.

    Hugs
    Marion

    #13219
    julianzchen
    Member

    Hi

    My 60 year old sister-in-law in Guangzhou, China, was recently diagnosed of advanced intrahepatic cholangiocarcinoma (ICC) and is in desperate need for treatment. The doctors there put her first on minimally invasive interventional chemo two weeks ago, and she is now also on Apatinib (an kinase inhibitor similar to Sorafenib or Nexavar). She is very thin and can walk, but the doctors there are not optimistic with the available treatment.

    I am keen on targeted therapy and the recent immuno-oncological therapy such as Keytruda or Opdivo, as I thought they may have less side effects and potentially can provide long term effect. Has anyone heard any report on this, including experimental therapy? What may be the biomarkers (FGFRII fission protein, PD-L1 for example) for patient group? Where are these clinical trials particular in Asia-Pacific region?

    Thank you!

    Julian, Boston, MA

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