Hi
My 60 year old sister-in-law in Guangzhou, China, was recently diagnosed of advanced intrahepatic cholangiocarcinoma (ICC) and is in desperate need for treatment. The doctors there put her first on minimally invasive interventional chemo two weeks ago, and she is now also on Apatinib (an kinase inhibitor similar to Sorafenib or Nexavar). She is very thin and can walk, but the doctors there are not optimistic with the available treatment.
I am keen on targeted therapy and the recent immuno-oncological therapy such as Keytruda or Opdivo, as I thought they may have less side effects and potentially can provide long term effect. Has anyone heard any report on this, including experimental therapy? What may be the biomarkers (FGFRII fission protein, PD-L1 for example) for patient group? Where are these clinical trials particular in Asia-Pacific region?
Thank you!
Julian, Boston, MA