Heat shock protein 90

Discussion Board Forums General Discussion Heat shock protein 90

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  • #64258
    Eli
    Spectator

    The study that Gavin linked was done in a dish.

    17-AAG is the name of the drug. Heat shock protein 90 (HSP90) is the target of the drug.

    17-AAG is also known as Tanespimycin. It was tested in a number of clinical trials:

    http://clinicaltrials.gov/ct2/results?term=tanespimycin

    None of these trials involved cholangiocarcinoma.

    This article says that Bristol-Myers (pharma company) has abandoned development of the drug:

    http://www.myelomabeacon.com/news/2010/07/22/tanespimycin-development-halted/

    #64257
    gavin
    Moderator

    Hi Anna,

    Is this what popped up on your FB page today?

    http://www.biomedsearch.com/nih/heat-shock-protein-90-inhibitor/22955701.html

    Have you tried using the search forum function at the top of the page to see what else is here on the site?

    Best wishes to you,

    Gavin

    #64256
    lainy
    Spectator

    Anna, Gavin just posted a link on this very question today.

    #7326
    pak001
    Spectator

    Anyone have any experience or knowledge of this target therapy: HSP90-
    heat shock protein 90? It popped up on my FB page and there’s not too much info that I can find on it’s significance on cholangiocarcinoma

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