Hyperbaric oxygen (HBO) therapy
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October 28, 2011 at 7:15 pm #54074marionsModerator
Susie….When my husband was on TPN we had asked the physician a similar question: “Do we feed the cancer.” His response: “We might however, we are keeping your husband viable.” You are doing the right thing by exploring the issue of oxygen with the experts.
All my best wishes,
MarionOctober 28, 2011 at 10:53 am #54073gavinModeratorThank you Marion, a break was needed but I will do some more digging later on this issue over the weekend.
Thanks Susie, glad that my links have given you more to look into. That is good to hear that your rad onc although not having experience with this treatment is keeping an open mind about it for you. I hope that your other onc has experience here, but if not, I hope she also has an open mind. It could well be worth speaking with Mayo if you are interested in looking further into this as they seem to be quite up to date on this treatment and say that they have one of the largest chambers in the US.
http://www.mayoclinic.org/hyperbaric-oxygen-therapy/
Yes I noticed that point about Cisplatin from the wiki page and as we know, Gem/Cis is the more standard chemo for CC patients. It would be imperative that you mentioned this to the doctors when you ask them about HBO and if that would be suitable for you. I too wonder why it is contraindicated and I will look more into this, and if you find anything out about this from your onc’s then please could you let us know what they say about that. I guess it could be the case that the wiki info about that is wrong, not saying that it is or anything but I wouldn’t take what wiki say as gospel here. I’ll post more links when I find them.
Hugs to you both,
Gavin
October 28, 2011 at 4:06 am #54072wallsm1SpectatorGavin!!!! You are my new hero!
I spoke with my radiation oncologist about the possibility of me heading over to the hyperbaric chamber after radiation. He said it’s not something he is familiar with and has never referred a patient to hyperbaric treatment. It is not something that is available at OHSU, the hospital I get treatment at. But, he also said just because it isn’t something he does, doesn’t mean it isn’t worth considering. The do have a hyperbaric chamber at a different nearby hospital where I live, so I think I will look into it at some point. I also plan to speak to my oncologist about it to see if she has any experience with it. Maybe even email the folks at Mayo to get their thoughts. I do have some concerns, though. I was recently on cisplatin, since it is the chemo of choice for us CC people, and I will also get a few more doses when I finish radiation. I wonder why it is contraindicated?? Also, I have concerns that if there are cancer cells left in my body are they going to feed of off this intense supply of oxygen?? I saw that was also mentioned in one of the links. It is interesting about the regeneration of biliary cells. My biggest fear with radiation is it will cause a biliary stricture and I will need a stent. If the hyperbaric treatment could prevent that, it would really be worth looking in to.
Things to think about!! (Like we didn’t have enough to think about)
Take care!!
SusieOctober 27, 2011 at 11:32 pm #54071marionsModeratorThanks Gavin. This is very helpful. Break time. You need it.
Hugs
MarionOctober 27, 2011 at 8:04 pm #54070gavinModeratorThats it for now, will try to find more info over the weekend.
Gavin
October 27, 2011 at 7:47 pm #54069gavinModeratorHyperbaric Oxygen Prevents Bacterial Translocation in Rats with Obstructive Jaundice.
http://www.springerlink.com/content/n3761610hp372308/
October 27, 2011 at 7:44 pm #54068gavinModeratorHyperbaric oxygen stimulates cell proliferation and normalizes multidrug resistance protein-2 protein localization in primary rat hepatocytes.
http://onlinelibrary.wiley.com/doi/10.1111/j.1524-475X.2005.00077.x/abstract
October 27, 2011 at 7:42 pm #54067gavinModeratorHyperbaric oxygenation promotes regeneration of biliary cells and improves cholestasis in rats.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3092876/
http://www.ncbi.nlm.nih.gov/pubmed/21633534
October 27, 2011 at 7:25 pm #54066gavinModeratorTreatment of gastrointestinal radiation injury with hyperbaric oxygen.
http://www.ncbi.nlm.nih.gov/pubmed/17393937
October 27, 2011 at 7:18 pm #54065gavinModeratorWiki pager here http://en.wikipedia.org/wiki/Hyperbaric_medicine
and they make the claim that patients should not undergo HBO if they are taking or have recently taken Cisplatin.
October 27, 2011 at 7:07 pm #54064gavinModeratorSeems that Mayo Clinic have an interest in this procedure and are doing some research into it, but are not currently running any trials right now.
“Researchers are currently examining the use of hyperbaric oxygen therapy for cancer and wound healing, such as:
Analysis of whether hyperbaric oxygen can enhance the effectiveness of radiation therapy to treat large tumors otherwise resistant to radiation and chemotherapy alone
Evaluation of the effects of hyperbaric oxygen on stem cell response in people who have diabetes or radiation injuries.”http://www.mayoclinic.org/hyperbaric-oxygen-therapy/research.html
October 27, 2011 at 7:02 pm #54063gavinModeratorThis is a good piece from the American Cancer Society –
October 27, 2011 at 6:21 pm #54062gavinModeratorHi Marion,
Good point. I will do some digging over the next few days and see if I can come up with anything.
Hugs,
Gavin
October 27, 2011 at 4:29 pm #54061marionsModeratorI wonder whether there is more detailed information re: the treatment for cancer patients? Scientific evidence?
October 27, 2011 at 10:48 am #5826gavinModerator“This information is about the use of hyperbaric oxygen therapy (HBO) for people with cancer. HBO therapy is sometimes used to treat a number of severe side effects of cancer treatment.”
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