Improve discrimination power of serum markers for diagnosis of cholang

Discussion Board Forums New Developments Improve discrimination power of serum markers for diagnosis of cholang

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  • #87694
    marions
    Moderator

    Duke…..the study comes from Thailand where people are infected with parasites and then develop bile duct cancer.
    Yes, there has been some interest in Serum markers, but in order to prove validity larger control groups are needed to provide us with conclusive evidence. We would also want to know whether patients from the Western World present with similar results. But, I don’t find it out of the realm of reality to gather this type of data worldwide. Unfortunately though the wheels of research move slowly and for us time is of the essence.
    Unlikely for insurance companies to cover the cost for blood test identifying the markers mentioned because, at this point results are unproven and speculative.
    Frustrating all the way around.
    Key points to look for in studies: This study is aimed to improve the diagnostic power of serum markers using the computational data mining technique to develop a combined diagnostic model that yielded the best diagnostic values for CCA.
    The C4.5 model “INDICATES” the combined markers of CCA-CA and ALP that produced the more precise diagnosis for CCA.
    Hugs,
    Marion

    #87693
    dukenukem
    Member

    Marion –

    Unfortunately, this only underscores the importance of early detection by checking for serum markers (alk-phos and associated carbohydrate antigen (CCA-CA) on a regular basis. Which requires that people need to understand the importance of this. More so, MDs and DOs need to make this a priority, especially when alk-phos goes up they need to check for CCA immediately. Which raises the costs for the insurance companies then for the insured.

    Duke

    #11140
    gavin
    Moderator

    Improve discrimination power of serum markers for diagnosis of cholangiocarcinoma using data mining-based approach.

    http://www.ncbi.nlm.nih.gov/pubmed/25863112

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