Induction of apoptosis in cholangiocarcinoma by an andrographolide ana

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    gavin
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    Induction of apoptosis in cholangiocarcinoma by an andrographolide analogue is mediated through topoisomerase II alpha inhibition.

    “These results suggest that andrographolide analogue 3A.1, a novel topo II inhibitor, has significant potential to be developed as a new anticancer agent for the treatment of CCA.”

    http://www.ncbi.nlm.nih.gov/pubmed/24360936

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