Is skin rashes a sign that chemo is working?

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  • March 20, 2012 at 12:20 am #59002
    jmgrisolia
    Member

    I dont know, she is on GEMOX. I don’t know if Tarceva has something to do with GEMOX. Her face… I am not sure. I hope chemo is working..

    March 19, 2012 at 11:37 pm #59001
    Eli
    Spectator

    Jose,

    Both Gemcitabine and Oxaliplatin can cause skin rash as a side effect. Is it a sign that chemo is working? I don’t know.

    I do know this. You need to keep the rash under control. Imagine for a moment that your sister cannot tolerate the rash. The doctors would have to reduce her chemo dose or give her a break from chemo. That’s not good, right? I think you need to discuss the rash with your sister’s oncologist.

    Best wishes,
    Eli

    March 19, 2012 at 9:38 pm #59000
    tiff1496
    Member

    Is she on Tarceva? If so, I would say yes!!! Is it on her face too?

    March 19, 2012 at 8:10 pm #58999
    jmgrisolia
    Member

    What should I think then? Is that a good sign?

    March 19, 2012 at 7:16 pm #58998
    tiff1496
    Member

    No way!
    In fact, when I seen Dr. Javle, the first thing he said to me is that he “loves seeing my face rash”. I think its from Tarceva.

    March 19, 2012 at 7:06 pm #58997
    Eli
    Spectator

    Gemcitabine and Oxaliplatin are not in the same category of drugs. They do not inhibit EGFR.

    ADDED: please note, skin rash might be a good sign in GEMOX as well. I just never heard about it. But then, I’m not a doctor.

    Best wishes,
    Eli

    March 19, 2012 at 6:56 pm #58996
    jmgrisolia
    Member

    Thank you Eli. She is taking GEMOX ( Gemcitabine + Oxaliplatino ). Does it fall into those categories?

    Jose

    March 19, 2012 at 6:45 pm #58995
    Eli
    Spectator

    Hi Jose,

    What chemo drugs does your sister take?

    What you said about skin rash applies to anti-EGFR chemo drugs such as Cetuximab (Erbitux) and Erlotinib (Tarceva). Here’s an article about this subject:

    Skin Rash Associated With EGFR Inhibitors: A Marker of Therapeutic Efficacy
    http://www.medscape.org/viewarticle/560280

    You might need to register for a free account to read the article.

    Best wishes,
    Eli

    March 19, 2012 at 6:14 pm #6528
    jmgrisolia
    Member

    Dear friends,

    I was once told in this discussion board that skin rashes are a sign that chemo is working well. Now I am seeing with hope that my sister has developed skin rashes all over her body and I wonder if this is a good news. In general I’d like to know your experiences about this.

    Thank you
    Jose

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