MATCH EAY131 Phase ll Study of P13K Beta Specific Inhibitor GSK2636771
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Patty…….sorry to hear this but good to hear the next plan of action is in place. Capecitabine (Xeloda) and irinotecan (CPT-11, Camptosar has shown effective in colon cancer and I expect the same good results for you. Fingers are crossed for limited and manageable side effects and please know, we are behind you, all the way
Hugs
MarionWell….the time has come that I have been ousted from the MATCH Phase 2 Study of the PK13 Specific Inhibitor GSK2636771. After being on it for four months, I had growth in the peritoneal lining and also a couple small nodules by my ovary that doubled in size. It sucks but we all know this cancer does suck!
I will go on Irinotecan, leucovoran, and xeloda and it will all be administered over a 48 hour period while wearing a fanny pack. This will happen every two weeks. Ahhhh…..I hate going back to chemo after I have not had bad side effects for so long….and they will more than likely be coming back to visit me. Get out the boxing gloves!
Patty……you are a trailblazer and No.1 in this treatment arm. Great to hear, Patty.
Sending tons of good luck and happy to know that you are plunging in a most perfect way.
Hugs,
MarionPatty,
Sending prayers, love and hugs your way! Hoping the side effects stay minimal and the results are amazing! Thanks for paving the way! Enjoy your summer sweet lady….everyday is a good day!!!!
Love,
MelindaI started a MATCH Phase ll Study of the P13K Specific Inhibitor, GSK2636771, in patients with tumors with P-TEN Loss by IHC on May 26, 2016. I take 400 mg of the trial pills once a day and so far the side effects are minimal. I have had slight stomach discomfort for about an hour after I eat and I have had diarrhea every day. I have not taken an anti diarrhea pill yet but getting close if it starts back up today. Other than that, so far so good. I am patient #1 in the trial enrolled in this arm of the MATCH Protocol at MD Anderson. I will have a scan towards the end of July to see if the magic pills are working. As the drug builds up in my body, I might expect other side effects….or maybe I will experience nothing but tumor reduction or disappearance of some tiny nodules.
It’s a beautiful, sunny day in southern Illinois and I will be out swimming, attending a backyard BBQ, and working in the landscaping! Every day is a good day~~~
Patty in Illinois
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