Measurement of serum carcinoembryonic antigen, carbohydrate antigen 19

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  • November 6, 2014 at 6:14 am #85364
    marions
    Moderator

    For more accurate results, I assume that data from a larger control group will have to be analyzed.

    November 5, 2014 at 9:01 pm #85363
    dukenukem
    Member

    I added a little excerpt:

    “No correlation was found between serum tumor markers and total bilirubin, aspartate aminotransferase (AST) and alkaline phosphatase (ALP). The sensitivity, specificity and accuracy were: CEA: 52%, 55%, and 58%; CA 19-9: 74%, 82% and 78%; CYFRA 21-1: 76%, 79% and 78%; MMP7: 78%, 77% and 80%, respectively. The combination of all serum markers afforded 92.0% sensitivity and 96% specificity in detecting cholangiocarcinoma, showing the highest diagnostic accuracy (94%).”

    Duke

    November 5, 2014 at 6:29 pm #10720
    gavin
    Moderator

    Measurement of serum carcinoembryonic antigen, carbohydrate antigen 19-9, cytokeratin-19 fragment and matrix metalloproteinase-7 for detecting cholangiocarcinoma: a preliminary case-control study.

    ” In conclusion, our preliminary results suggest that the measurement of all four biomarkers together can help in the early detection of cholangiocarcinoma.”

    http://www.ncbi.nlm.nih.gov/pubmed/25368272

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