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  • #92519
    marions
    Moderator

    I have learned that end stage liver disease (intrahepatic CCA) most often includes jaundice.

    This is different from the initial, late stage diagnosis of perihilar (Klatskin tumor) where jaundice is related to blockage of bile ducts.

    Hugs
    Marion

    #92518
    daisy1
    Participant

    Mum eventually had jaundice but mildly. Her eyes went a bit yellow as did her skin but nothing major. She also had mild itching for a few days.
    I was a bit cross with her doctor who did a blood test yesterday to see if her nausea was a result of her morphine dose. I didn’t know they were testing her as I wasn’t there, just saw the bandage on her arm later. I told the doctor that if he researched her disease he would know the vomiting was caused by biliary obstruction, proven when I stopped her food intake. Anyway, the blood test showed her kidney function wasn’t too bad so perhaps that’s why her jaundice isn’t too bad.

    #92517
    marions
    Moderator

    helpformom….thanks for chiming in and confirming that in your Mom’s case (intrahepatic CCA) jaundice is not a factor. This is different for extrahepatic CCA (Klastskin tumor) in where jaundice most often is caused by a blockage in the biliary tree which then leads to the diagnosis of cholangiocarcinoma.
    Thanks again,
    Hugs,
    Marion

    #92516

    I believe it has a lot to do with where the mass is and also how well your kidneys are functioning.
    My mother has ICC (awaiting biopsy confirmation) and does not have jaundice or itching or other symptoms that come along with an abundance of bilirubin and blockage. Her mass is not blocking any major ducts.

    #92515
    marions
    Moderator

    Daisy……I like to add to the excellent explanation provided by hercules, that early diagnoses with hilar cholangiocarcinoma (Klatskin) tumor most often, but not always is due to biliary obstruction.
    End stage liver disease, in where the liver becomes scarred (Cirrhosis) it no longer can heal itself.
    Others may have more to do add to this important questions. (I hope.)
    Hugs,
    Marion

    #92514
    hercules
    Moderator

    Daisy, everyone is a bit different but some become jaundiced and some do not, some peoples kidneys can keep up removing bile ( bilirubin ) from the bloodstream while others can not, therefor they become yellow colored in the eyes, skin, Urine is dark yellow orange when bilirubin is present . I believe this is what occurs from my observations and reading here.

    #12550
    daisy1
    Participant

    After researching this evil disease, I keep finding articles that talk of jaundice being the number 1 symptom. What does it mean when jaundice is not present?

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