Hi,
Sorry, I do not know the answer, in general ,if you can tolerate the drug and it works on the cancer, you can continue to take it until otherwise.
The problem is that the accumulative toxicity like peripheral neuropathy sooner or later will force patients to stop treatment .And the toxicity will last much longer than you expected depending on the total accumulated dose.( due to the long term retention period of the platinum drug is between 8-75 month; oxaliplatin has three t1/2 life [half life] at 0.26 hr,16.3 hour and 273 hr.)
Therefore the toxicity may show up within the first 1-2 hour of each infusion, as acute peripheral neuropathy which can be resolved within hours of onset;(about 38 % of pts);or the delayed type will show up in>14 days and the symptoms will be persistent (about 48% pt who are on 5FU+oxaliplatin)
Other patients cannot continue oxaliplatin included those whose will develope low platelets—-bleeding concern( 64-71%) and white blood cell count—eg.infection concern(73-81% in study done for colon cancer on long term treatment.)
God bless.