Progranulin and cholangiocarcinoma: another bad boy on the block
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Interleukin-6-driven progranulin expression increases cholangiocarcinoma growth by an Akt-dependent mechanism.
“ConclusionsEvidence is presented for a role for progranulin as a novel growth factor regulating cholangiocarcinoma growth. Specific targeting of progranulin may represent an alternative for the development of therapeutic strategies.”
http://www.ncbi.nlm.nih.gov/pubmed/22068162?dopt=Abstract
Progranulin and cholangiocarcinoma: another bad boy on the block!
“The authors suggest that PGRN may be a potential target for the development of novel therapeutic strategies for CCA.”
http://gut.bmj.com/content/early/2011/11/07/gutjnl-2011-301518.extract
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