Studies are underway to determine the effectiveness of radiation in Cholangiocarcinoma. We should soon receive data derived from a clinical research study treating unresectable intrahepatic CCA treated with Gemcitabine and Cisplatin with added radiation treatment.
https://clinicaltrials.gov/ct2/show/NCT02200042
A retrospective study (evaluating response to a previously treated patient group) confirmed that larger tumors not eligible for surgical resection and combined with higher doses of radiation show equal response rates to those with surgical resection.
“Ablative Radiotherapy Doses Lead to a Substantial Prolongation of Survival in Patients With Inoperable Intrahepatic Cholangiocarcinoma: A Retrospective Dose Response Analysis”
Due to Journal of Clinical Oncology proprietary rights, I am unable to post neither the link to the abstract nor am I able to download the publication on this site.
However; anyone can sign up with PATIENT ACCESS and request the information with this link:
https://s100.copyright.com/AppDispatchServlet?publisherName=ASCO&publication=jco&title=Ablative%20Radiotherapy%20Doses%20Lead%20to%20a%20Substantial
To learn more about the effectiveness of higher dose radiation, you may want to download this video from our site:
http://cholangiocarcinoma.org/new-upcoming-webinar-the-emerging-role-of-radiation-for-intrahepatic-cholangiocarcinoma-higher-doses-lead-to-improved-survival/
Hugs,
Marion