Severe Nausea

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  • #50808
    peony
    Member

    Thank you all for your answers. The nausea is from the chemo and we have spoken to the doctor about alternate meds. He thinks his body just can’t handle the cysplatin any longer and is going to take him off of it for now as he desperately needs a break.
    Nancy, we did seek a 3rd opionion and he is not a canditate for surgery. So we’ll just keep moving along and trying different things.
    I’m going to forward your suggestions on the meds to the doctor and see what he says. Kathy, thanks for the tip on the ulcer I will ask him about that as well.
    Again, thanks everyone. Coming to this site and reading these entries really helps to keep me strong (along with the lexapro :)).

    Peony

    #50807
    kathyb
    Member

    Peony,

    This may not apply, but I had constant nausea during my first chemo and radiation treatments. Nothings helped. Tried many medicines. Turned out I had developed an ulcer on my esophagus from treatment. After high doses of prilosec for 4 days, the nausea was gone.

    Hope an answer/solution can be found soon.

    Kathy

    #50806
    pcl1029
    Member

    Hi, sorry, I have to copy and paste this info. for you after I answered another member for N/V problem.

    Older anti-nausea/vomiting drugs included
    1. Group 1(antidopaminergics).- prochloperazine;promethazinereglan.
    2. Group 2 like cyclizine, meclizine,dimenhydrinate, benadryl,scopolamine and tigan are belong to anticholinergics group.
    3.Group 3 like corticosteroids (dexametason),cannabinoids and hydroxyzine are belongs to the miscellaneous group.
    Try to ask your doctor to switch to another group of med if the one your father took is not working or try a combination from different groups.
    or use newer ones like the following;
    New antiemetics such as the
    1. 5-HT3 receptor antagonist group- ondansertron (Zofran), dolasetron(Anzemet), granisertron (Kytril)and palonosetron(Aloxi) and
    2. the NK1 receptor antagonist like aprepitant (Emend) and others are on the market ;they come as an oral capsule or tablet.Emend has to be taken with other antiemetics and on schedule for the maximum anti -nausea/vomiting.
    On one of the ASCO 6/2011 poster session abstract#9091,indicated
    “significant clinical benefits in favor of palonosetron were also seen in the delayed and overall time periods on the number of emetics episodes and the severity of nausea.”when compare to the other 3 5-HT3 receptor antagonists.

    Also for anticipatory nausea;XanaX 0.5mg-1mg with Benadryl 25mg-50mg 20-30min before chemo works well with me.
    Ginger root has been used for a long time for controlling nausea in Asia. a study of 644 patients were randomly assigned to placebo or ginger (0.5-1gm capsule twice daily for six days) ;starting three days prior to the first day of the next 2 cycle of chemo treatment.all of the patients received 5-HT3 receptor antagonist on day 1 of all cycles.Significant reduction in nausea throughout day 1 of the chemo cycles was observed.
    To find out the cause of nausea and vomiting besides thinking it is only comes from the chemo is important too. (ie; is the patient on antibiotics too?does the patient have no bowel movement?Is he on too much opiates?
    God bless.

    #50805
    nancy246
    Spectator

    Hi Peony, I have my daughter and her boyfriend visiting. They both have degrees in nursing and work at a large hospital. I posed your question to them. They suggest trying maxevan for nausea and motilium (also known by domperidone) for the bloating. Motilium is taken with meals and it helps move food through the digestive tract easing bloating. Hope this helps. Shannon said different people respond to different meds.
    (There is also good old gravol for nausea but it does cause drowsiness.)
    Have you asked your doctor about the weakness in the legs? It could be the spine mets acting up, but as Lainy said he could just be tired out.
    Wondering if they are still looking at surgery for your husband? Did you get that third opinion?
    I do hope he is feeling better soon. It’s not pleasant feeling bloated and nauseous.
    Hugs. Nancy

    #50804
    marions
    Moderator

    Peony……you would want to speak with the physician about this: the nausea and bloating may be related to undigested food in his stomach. Does your husband have regular bowel movements? If not then you would want to discuss with his doctor the use of food softeners. Also, enzymes will aid in the digestion. Moving around and if possible small walks will encourage the digestive tract. Also, you might want to have him eat small meals several times per day. When has he had his blood test and scan last?
    Please, keep us posted.
    All my best wishes,
    Marion

    #50803
    lainy
    Spectator

    Hi Peony, I am so sorry to hear your husband is feeling so bad. Is the nausea from Chemo? If not, that and the bloating could be related and he should be seen by his doctor immediately. I would think that the nausea is wearing him out and his legs could be weak from just being worn out. The drugs you mention are all top notch so I am wondering what his doctor says about it.

    #5253
    peony
    Member

    My husband is experiencing severe nausea and bloating.
    He’s tried Compazine, zofran, amend and marinol and none of them seem to offer any relief.
    Any suggestions Anyone!

    Also has anyone experienced weekness in their legs? what is that all about?

    Peony

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