Where do we go from here?

My husband, Tim, is a 50 yr old non-smoker, non-drinker, former DIV 1 college athlete who still ran 15 miles/week and had no major health issues. The past Christmas eve, I rushed him to the ER because he was vomiting blood. They said he had a bleeding ulcer, acute pancreatitis, and gall stones. After CAT scan and MRI they found the mass, diagnosed cholangiocarcinoma and transferred him from our local community hospital to Thomas Jefferson University Hospital in Philadelphia. After placing a plastic stent and doing a biopsy on a nearby lymph node, they told us the liver was non-resectable and oh, by the way, he also has cirrhosis of the liver. It turns out he has a genetic condition causing Alpha one antitrypsin deficiency which caused the cirrhosis. Knowing surgery was our only hope for a cure we got a second and third opinion from Univ of Penn and Johns Hopkins. They both concurred with original opinion. After extreme emotional turmoil, we prayed that Tim would get selected for the experimental arm of a photodynamic therapy clinical trial in the hopes it would buy us some time so that he could see our youngest graduate from high school and maybe go on a few trips we had planned to do after retirement. Tim did get into the trial. In late January, during an ERCP they performed the PDT and placed two plastic stents in the biliary ducts. The next week he began chemo with Gemcitabine and Cisplatin. He tolerated the first 2 treatments well. By the 3rd treatment he began to retain fluid in his legs and abdomen. After the 4th treatment they had to stop chemo and perform a paracentesis removing 6.5 liters of fluid. In late March he suffered deep vein thrombosis and multiple pulmonary embolisms. He was hospitalized for two weeks in an attempt to get the acute ascites under control. He no longer could tolerate the chemo and in June they performed an ERCP to place a permanent metal stent. He has now lost 40 pounds, is on a low salt diet, taking diuretics, and receiving a paracentesis about every 11 days. The liver failure has taken precedence over the cancer and the oncologist agrees that further chemo would probably only exacerbate the liver problems. He sleeps about 14-16 hours/day, has balance issues, periods of pain and nausea, can’t get up without help, and only leaves the house for doctor visits. We initially had a Plan B of proton beam radiation and were pursuing an appeal to the insurance company, but honestly now don’t want to introduce further toxicity into his system. In reading other people’s posts on this site, I wonder about Keytruda. Our only thought at this point is the possibility of immunotherapy. Our concern is that could it make things even worse for him, now. His quality of life is already poor and I don’t want to make it worse. While his slow deterioration has been extremely difficult for me to watch, it has been devastating for him to live through. Only our faith in God and the love and support of our incredible family and friends has sustained us thus far. Is he even eligible for the treatment? Who would you recommend we contact for information about an evaluation?