Keivan

Hi Mary

Thank you for your explanation and your time

My mother had 18 sessions WBRT (Whole brain radiotherapy), She has one brain met located in deep left temporal lobe (thalamus) which is not operable, and strange thing is that the primary tumor in gallbladder wall was 1.5 cm but brain met is 4 cm, Six months after radiotherapy tumor shrink-ed and its now 3 cm
Do you mean the radiation would completely treat the brain metastases?
I’ve heard that Avastin is being used as a treatment option for the primary brain tumors like Gliblastoma, This drug decrease  swelling of  the brain, I wanted to know if it works for brain mets as well?

We live outside of U.S and there is no any ongoing clinical trials around us, As you know most of clinical trials regarding Bile duct cancer is running in U.S

My mother had tumor profiling (genetic test) for PDL-1 and BRAF and both were negative
recently we did some more genetic test including MSI, HER2, IDH-1 and FGFR2 and currently we are waiting for the results
My mother had a brain biopsy 9 months ago and they found out that her brain tumor is HER2 positive, I hope she can benefit from targeted therapy

Warm Regards