pattic

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  • in reply to: 3 years- non-resectable #15105
    pattic
    Spectator

    Good morning all,
    So begins a new year. I am new to this although been reading many entries. My 60yr old husband was dx June 14, 2016 with inoperable intrahepatic choliangiocarcinoma, A 10cm+ in right lobe. Initial discovery was thru elevated alkainline phosphatase lab. Then imaging, then confirmation needle bx. July 12 had y90. Tolerated well, no post op symptoms, back to work next day. Following week flew to Houston, md anderson, july 28th started gem/cis, md anderson protocol, every 14 days. In the interim had radio frequency ablation on what turned out to be 4 small sites( less than 2.5cm) 2 in right lobe 2 in left lobe. Because it took close to 3 hrs overnight stay in hospital. Post op was uncomfortable for several days but back to work 9/30 2nd pet scan no light up. MRI with contrast 11/3/2016 docs words, “remarkable shrinkage”. Had 11th chemo 12/29/16, aside from only recently some fatigue 5th day from chemo, tolerating well. His afp tumor marker on dx 394. As y90 worked it went up to 551, then 794, I believe lysing into bloodstream. Then down it went to 87, 25, since October has been in normal range 7.0, 6.9, 8.0 As most of you know tumor markers are not definitive but normal range is encouraging. Foundation One IDH2 is his predominate mutation. We believe strongly the y90 was huge contribution to shrinkage of large tumor and chemo controlling microscopic ca cells. In our hospital system here in broward cty fl our surgical oncologist considers him a good possibility for resection of right lobe. Not sure if sx would have clear margins, right and middle hepatic veins, still some encasement. Our interventional radiologist strongly supports possible sx choice. My husband continues to work full time. We are grateful 6 mths after dx still here. Both of us in medical fields. Any comments are appreciated.

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