pcl1029

Hi,Trevor,
I don’t think so.Get stronger with the TPN first,the rest will come much easier.
God bless.

Hi,Sissy,
I am a patient and have the same CC descriptions as yours .I had my left lobe removed and RFA(ablation )done at the 2 spots in my right lobe with clear margin 2 years ago; Gemzar chemo for 14 months as adjuvant therapy.

Usually when the surgeons(liver specialist) perform resections,they will use intra-operative ultrasound to detect the CC they cannot see in the liver and do ablations (RFA) to burn the tumors dead unless the tumors are too close to vital organs.So you should not worry too much about the clear margin .
The chemo you will receive most likely is the adjuvant therapy consist of either Gemzar or a combination of Gemzar plus one of the platin group agents like (Cisplatin, oxaliplatin);Or 5Fu.
I am not a doctor,but I know you will do fine since the age factor is on your side.
The prednisone you take is not the risk factor that contributed to the disease CC.

For chronic prednisone user like you, and if your dose of prednisone >5mg daily, may I suggest you should talk to your GP to order tests like Bone mineral density(BMD),preferably of the spine;lipid profile and serum glucose to monitor and prevent osteoporosis.and you should take calcium and vitamin D supplementation daily as suggested by your doctor.

Stem cell treatment of any sort–outside of bone marrow transplants and a few other rarely used treatments–are not anywhere close to being therapeutic use.(from Arthur Caplan Ph.D.-a msnbc contributor)
The ONLY and FIRST stem cell therapy product that just got FDA approved in June 2011 for “improvement of the appearance of moderate to severe nasolabial fold wrinkles in adults “is Laviv (Azficel-T) . In short,there are no approved and effective stem cell treatment or protocol for CC in the States.

Sometimes if you treat CC as a chronic disease like hypertension or diabetes
,you will feel much better and will provide yourself more positive energy to take care of your illness.
CC is a long and winding road that required courage ,patience and knowledge to navigate on it . Don’t worry,you will be fine.As the bible saids in 1.Corinthians 10:13,”.

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God is faithful,and he will not let you be tested beyond your strength,but with the testing he will also provide the way out so that you may be able to endure it.”
God bless.

Hi,Gavin,
Besides the obvious risk factors for ICC.I cannot agree more on this paper.
37%(a 2 fold )increase in HCC and 30%(1.56 fold) increase in ICC in their findings.

I myself is a chronic hepatitis B carrier since birth,and high cholesterol (50-100% higher than the norm)runs in my family;my triglycerides is about 50-100% higher than the norm. But I belongs to the few who cannot take the statins ;so I ignore the whole thing for about 10 years .this is why after the 2nd resection;I change my game plan;besides eating more fruits and veggie,I have started on Tricor for triglycerides,fish oil 4gm for cholesteol,Baraclude for Hep.B ;Protonix for acid reflux and may add Questran for binding the bile acid to decrease the absorption back to the biliary system.I also learn one thing from my sister-in-law “central obesity” is real risk factor too esp. if the family have diabetes history.
So this report is not just a report but rather an accurate assessment of the risk factor for the raising of CC population from my personal point of view.

I will not be surprised the CC figure will be higher in America in the next 10 years if people continue to eat and pay no attention to their weight even they know about the family diabetes history.I apologize to those people now first if the following message will upset you,I am sorry.My intention is medical awareness in general,not personal.
In my profession in the 1980s ,200lbs or 100kg patients are consider “healthy”(you should know what I mean about healthy) ,nowadays 200-250lbs (125kg)are very common and of course 300lbs(135kg) are not uncommon; and 400-600lbs (average 500lb or 230kg)are not rare. I saw a 700lb?”before I had the second resection;but if you consider most of them had underlining diseases,diabetes hypertension, respiratory problems etc. What can they expected as a patient if they don’t take care of them self first at home.
You just take a look at the increase of the WIDTH of the wheel chair the hospital used or ask nurses you know and you will understand the obesity problem in the States.
Good article.
God bless.

Hi,Wendy,
As always this is for your info. only.Consult specialists first before changing treatment plan is a must.
They have already found the source and switched the ABX to Tigercillin-Cluv. which is indiciated for biliary sepsis.so you are in good hands.
Keep Nexium or Protonix twice daily for a while or at least once a day even after discharged. I take Protonix once daily for at least six month to prevent GERD or to decrease the acid reflux which over the long period of time can make the inflammation of the digestive system worse and I do not want that.
Kepp us inform so we can help others too.
God bless.

Hi,
After I read your previous entries, and based on what my experience of it(no side effects,may be subtle pain ;your mom may be a bit different since she had 30 or so little lesions plus a 5cm one).I will go along with JH recommendation.
23hr hospital observation may be required or she can go home the same day depends on JH protocol.
Chemoembro with cisplatin,mitomycin and Adriamycin alone or in combination mix with an oily vehicle or beads to inject into the liver via the groin under CAT SCAN direction angiogram. RFA may be use later to kill the tumor off or the chemoembro can be repeated to get the maximum effects out of it a month later.

Radition with Yttrium 90(SIR-Spheres)using beads of 32 microns in size to carry the Yttrium 90,injected into the hepatic artery using CAT SCAN as a guide.
the beads lodge in the vasculature of the tumors;The beta radiation remains localized,penetrating a mean of 2.4mm in tissue and destroy the tumor cells.Half life of the radiation=2.7days and most of them(>97% )is delivered in weeks,with almost no radiation remaining after 1 month.-company info.by Sir-Spheres.provided at the ASCO 6/2011 convention at Chicago.

“The ideal patient to use this method would have the following:(-From SIR-Spheres company booklet 268-M-Leaf REV.1 0910)
1. Liver-only or liver-predominant disease.
2. Good performance status.
3. Adequate Liver function
4. Remaining Chemotherapy options.
and this radiation procedure has no therapeutic effect on EXTRA hepatic disease.”

As far as I can understand at this moment, most of the time this radiation procedure is used in combination with chemo to achieve or prolong “time to progression” of chemo alone treatments or in chemotherapy refractory patients.
Keep in touch so we can also help others.
God bless;.

Hi,Wendy,
since I did not hear from you.this is what I may suggest and
As always,consult physicians is a must before any changes of treatment plans.

Since I do not know about the origin (the bacteria)of the sepsis infection
they should do blood cultures on your dad and find it out by now.
“Hospital acquired pneumonia” is also a concern if your dad stayed in the ICU for too long.
For UNKNOWN origin of the sepsis in which patient are not neutropenic (low WBC),no hypotension ,febrile and not life threatening:
The primary antibiotics (ABX)are the carbapenems such as Ertapenem or Primaxin in addition to Vancomycin.If the source of sepsis is BILIARY (eg, from the stents),then the primary antibiotics will be piperacillin-taz (Zosyn)or ticarcillin-clav in the antipseudomonial penicillins group.Levaquin or Cipro plus metronidazole(Flagyl) or Cefotaxime plus metronidazole can be used as alternative to the primary.they all are given as IVPB.
Do not worry about the creatinin,the pharmacist should adjust the antibiotics dose based on the creatinin clearance of the patients daily.Even if the patient is on hemodialysis. so check the hospital out to see they have done the blood and urine culture and find out what bacterias are,then check what antibiotics they used and whether the doctors or pharmacist adjust the dose daily for the ABX. and then should be fine.
Taking care of the infection is the fist priority NOW. after your dad recover for sepsis as you mentioned or suspected;then choose your oncologists ,we will talk later about this.
BTW, please try to read the “the Ultra sound CT scan MRI and PET/CT” in our experience forum,this will provide you help in understanding FDG uptake
in PET/CT scan and know how to talk and understand the doctor’s comment about your dad. You dad is only stage II and young.You need a lot of knowledge to help him to fight the CC.
As I always say, knowledge,patience and courage are need on the long and winding journey to help your father to get well.
God bless.

Hi,Wendy,
As always,this is for information purpose only;consult doctors first is a must
May I ask the name of the hospital your father is at now in Phillipines?
and what are the antibiotics and meds he is on now? I will go to bed soon but I will answer you if you give me the above info. within an hour. ok.
God bless.