Biliary Tract Cancer Cell Lines & PDX Resources

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These cell lines are available under MTA’s from the designated repositories.  Please click on the links in the right column for contact information of each repository and specific instructions for requesting cell lines.

NAMECell line or PDX SOURCEDESCRIPTIONLINK or contact person
EGI-1DSMZ (ACC-385)EHCCAhttps://www.dsmz.de/catalogues/details/culture/ACC-385.html?tx_dsmzresources_pi5%5BreturnPid%5D=192
HuCCT1JCRB (JCRB0425)IHCCAhttp://cellbank.nibiohn.go.jp/legacy/celldata/jcrb0425.htm
KKU-100JCRB (JCRB1568)Human poorly differentiated cholangiocarcinoma cell line established from biliary tract.http://cellbank.nibiohn.go.jp/~cellbank/en/search_res_det.cgi?ID=7096
KKU-M214/M213JCRB (JCRB1557)/(JCRB1556)IHCCAhttp://cellbank.nibiohn.go.jp/~cellbank/en/search_res_det.cgi?ID=7076
MMNK-1JCRB (JCRB1554)Highly differentiated immortalized human cholangiocyte cell line (non-cancer)http://cellbank.nibiohn.go.jp/~cellbank/en/search_res_det.cgi?RNO=JCRB1554
OZJCRB; JCRB1032IHCCA (Derived from metastatic site: Ascites)http://cellbank.nibiohn.go.jp/legacy/celldata/jcrb1032.htm
SNU-1079KCLB (01079)IHCCAhttp://cellbank.snu.ac.kr/english/sub/catalog.php?s_cellid=91&page=detail_info&CatNo=59&strQ=01079
SNU-1196KCLB (01196)EHCCAhttp://cellbank.snu.ac.kr/english/sub/catalog.php?s_cellid=162&page=detail_info&CatNo=59&strQ=01196
SNU-308KCLB (00308)GBChttp://cellbank.snu.ac.kr/english/sub/catalog.php?s_cellid=92&page=detail_info&CatNo=59&strQ=00308
SNU-478KCLB (00478)BTC, ampulla of vaterhttp://cellbank.snu.ac.kr/english/sub/catalog.php?s_cellid=95&page=detail_info&CatNo=59&strQ=00869
SNU-869KCLB (00869)BTC, ampulla of vaterhttp://cellbank.snu.ac.kr/english/sub/catalog.php?s_cellid=95&page=detail_info&CatNo=59&strQ=00869
RBERCB (RCB1292)IHCCAhttp://www2.brc.riken.jp/lab/cell/detail.cgi?cell_no=RCB1292
SSP-25RCB (RCB1293)IHCCAhttp://www2.brc.riken.jp/lab/cell/detail.cgi?cell_no=RCB1293
TFK-1RCB (RCB2537)EHCCAhttp://www2.brc.riken.jp/cache/cell/RCB2537
TGBC1TKBRCB (RCB1129)GBC (Derived from metastatic site: Lymph node)http://www2.brc.riken.jp/lab/cell/detail.cgi?cell_no=RCB1129
TKKKRCB (RCB1907)IHCCAhttp://www2.brc.riken.jp/lab/cell/detail.cgi?cell_no=RCB1907
YSCCCRCB (RCB1549)IHCCAhttp://www2.brc.riken.jp/lab/cell/detail.cgi?cell_no=RCB1549
HuCCT1  Dr. Lawrence Kwong lkwong@mdanderson.org
OZ  
SNU-1079  
RBE  
SSP-25  
TKKK  
CC-LP-1  
CC-SW-1  
Huh-28  
SNU-245  
SNU-1196  
WITT  
TFK-1  
Koch  Dr. Sergio Gradilone sgradilo@umn.edu
Hucct-1  
H69  
Huh-28 IHCCADr. Giovanni Brandi giovanni.brandi@unibo.it 
Dr. Simona Tavolari simona.tavolari@unibo.it
TFK-1 EHCCA
SNU-245 EHCCA
SNU-1079 IHCCA
WITT EHCCA
EGI1 EHCCA
H69 Immortalized cholangiocytes
HuCCT1  Dr. Vaibhav Sahai vsahai@med.umich.edu
TFK-1  
JCRB: Japanese Collection of Research Bioresources Cell Bankhttp://cellbank.nibiohn.go.jp/english/
DSMZ: Deutsche Sammlung von Mikroorganismen und Zellkulturenhttps://www.dsmz.de/
KCLB: Korean Cell Line Bankhttps://cellbank.snu.ac.kr/main/index.html
RCB RIKEN Cell Bankhttp://www2.brc.riken.jp/lab/cell/search.php
Cholangiocarcinoma cell linesDr. Xin Wei Wang xw3u@nih.gov
Cholangiocarcinoma cell lines for Kras, SMAD4, P53, and ARID1A mutationsDr. Aram Herzel aram_hezel@URMC.rochester.edu
Cholangiocarcinoma cell lines and 30 human cholangiocarcinoma PDX modelsDr. Gregory Gores gores.gregory@mayo.edu
Cholangiocarcinoma cell lines and cholangiocarcinoma PDX modelsDr. Lewis Roberts Roberts.lewis@mayo.edu
Dr. Fowsiyo Ahmed ahmed.fowsiyo@mayo.edu
Cholangiocarcinoma PDX modelsDr. Funda Meric-Bernstam fmeric@mdanderson.org
Cholangiocarcinoma PDX modelsDr. Sergio Gradilone sgradilo@umn.edu
Cooperative Human Tissue Network (CHTN)*https://www.specimens.cancer.gov/details/283/?c2=224
Brain and Body Donation Program*https://www.specimens.cancer.gov/details/494/?c2=224
Gundersen Biobank*https://www.specimens.cancer.gov/details/207/?c2=224
Hollings Cancer Center Biorepository & Tissue Analysis Shared Resource*https://www.specimens.cancer.gov/details/357/?c2=224
NCI DTP DCTD Tumor Repository*https://www.specimens.cancer.gov/details/646/?c2=224
OHSU Knight BioLibrary*https://www.specimens.cancer.gov/details/295/?c2=224
Ontario Tumour Bank*https://www.specimens.cancer.gov/details/620/?c2=224
University of Iowa Tissue Procurement Core Facility*https://www.specimens.cancer.gov/details/293/?c2=224
 

These cell lines are available under MTA’s from the designated repositories.  Please click on the links in the right column for contact information of each repository and specific instructions for requesting cell lines.

We would like this resource to be comprehensive and widely available to those who are interested in research. It is our desire to provide interested researchers with as much validated information as we can to expand the collaborative CCA research community. If you are aware of available resources not listed, please contact us.

A number of human biliary tract cancer cell lines have been reported in the literature, including cell lines derived from intrahepatic cholangiocarcinoma, extrahepatic cholangiocarcinoma, and gall bladder cancer. The table lists commonly used biliary tract cell lines available from repositories. Also listed is an immortalized but non-transformed human bile duct-derived cell line.

If you have additional information about human biliary tract cancer cell lines, please contact info@cholangiocarcinoma.org

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Cholangiocarcinoma (CCA) Mutations

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CCAMutations