Biliary Tract Cancer Cell Lines & PDX Resources

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These cell lines are available under MTA’s from the designated repositories.  Please click on the links in the right column for contact information of each repository and specific instructions for requesting cell lines.

CELL LINE NAME SOURCE DESCRIPTION LINK (will open in a new window)
EGI-1 DSMZ
(ACC-385)		 Extrahepatic cholangiocarcinoma https://www.dsmz.de/catalogues/details/culture/ACC-385.html?tx_dsmzresources_ pi5%5BreturnPid%5D=192
HuCCT1 JCRB (JCRB0425) Intrahepatic cholangiocarcinoma http://cellbank.nibiohn.go.jp/legacy/celldata/jcrb0425.htm
HuCCT1 RCB
(RCB1960)		   http://www2.brc.riken.jp/lab/cell/detail.cgi?cell_no=RCB1960&type=1
HuH-28 RCB
(RCB1943)		   http://www2.brc.riken.jp/lab/cell/detail.cgi?cell_no=RCB1943&type=1
KKU-100 JCRB (JCRB1568) Human poorly differentiated cholangiocarcinoma cell line established from biliary tract. http://cellbank.nibiohn.go.jp/~cellbank/en/search_res_det.cgi?ID=7096
KKU-M214/M213 JCRB (JCRB1557)/ (JCRB1556) Intrahepatic cholangiocarcinoma http://cellbank.nibiohn.go.jp/~cellbank/en/search_res_det.cgi?ID=7076
MMNK-1 JCRB (JCRB1554) Highly differentiated immortalized human cholangiocyte cell line (non-cancer) http://cellbank.nibiohn.go.jp/~cellbank/en/search_res_det.cgi?RNO=JCRB1554
OZ JCRB; JCRB1032 Intrahepatic cholangiocarcinoma. Derived from metastatic site: Ascites http://cellbank.nibiohn.go.jp/legacy/celldata/jcrb1032.htm
SNU-1079 KCLB (01079) Intrahepatic cholangiocarcinoma http://cellbank.snu.ac.kr/english/sub/catalog.php?s_cellid=91&page=detail_info&CatNo=59&strQ=01079
SNU-1196 KCLB (01196) Extrahepatic cholangiocarcinoma http://cellbank.snu.ac.kr/english/sub/catalog.php?s_cellid=162&page=detail_info&CatNo=59&strQ=01196
SNU-308 KCLB (00308) Gallbladder carcinoma http://cellbank.snu.ac.kr/english/sub/catalog.php?s_cellid=92&page=detail_info&CatNo=59&strQ=00308
SNU-478 KCLB (00478) biliary tract cancer, ampulla of vater http://cellbank.snu.ac.kr/english/sub/catalog.php?s_cellid=95&page=detail_info&CatNo=59&strQ=00869
SNU-869 KCLB (00869) biliary tract cancer, ampulla of vater http://cellbank.snu.ac.kr/english/sub/catalog.php?s_cellid=95&page=detail_info&CatNo=59&strQ=00869
RBE RCB (RCB1292) Intrahepatic cholangiocarcinoma http://www2.brc.riken.jp/lab/cell/detail.cgi?cell_no=RCB1292
SSP-25 RCB (RCB1293) Intrahepatic cholangiocarcinoma http://www2.brc.riken.jp/lab/cell/detail.cgi?cell_no=RCB1293
TFK-1 RCB (RCB2537) Extrahepatic cholangiocarcinoma http://www2.brc.riken.jp/cache/cell/RCB2537
TGBC1TKB RCB (RCB1129) Gallbadder carcinoma (Derived from metastatic site: Lymph node) http://www2.brc.riken.jp/lab/cell/detail.cgi?cell_no=RCB1129
TKKK RCB (RCB1907) Intrahepatic cholangiocarcinoma http://www2.brc.riken.jp/lab/cell/detail.cgi?cell_no=RCB1907
YSCCC RCB (RCB1549) Intrahepatic cholangiocarcinoma http://www2.brc.riken.jp/lab/cell/detail.cgi?cell_no=RCB1549
JCRB: Japanese Collection of Research Bioresources Cell Bank http://cellbank.nibiohn.go.jp/english/
DSMZ: Deutsche Sammlung von Mikroorganismen und Zellkulturen https://www.dsmz.de/
KCLB: Korean Cell Line Bank https://cellbank.snu.ac.kr/main/index.html
RCB RIKEN Cell Bank http://www2.brc.riken.jp/lab/cell/search.php

These cell lines are available under MTA’s from the designated repositories.  Please click on the links in the right column for contact information of each repository and specific instructions for requesting cell lines.

We would like this resource to be comprehensive and widely available to those who are interested in research. It is our desire to provide interested researchers with as much validated information as we can to expand the collaborative CCA research community. If you are aware of available resources not listed, please contact us.

A number of human biliary tract cancer cell lines have been reported in the literature, including cell lines derived from intrahepatic cholangiocarcinoma, extrahepatic cholangiocarcinoma, and gall bladder cancer. The table lists commonly used biliary tract cell lines available from repositories. Also listed is an immortalized but non-transformed human bile duct-derived cell line.

If you have additional information about human biliary tract cancer cell lines, please contact info@cholangiocarcinoma.org

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Cholangiocarcinoma (CCA) Mutations

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CCAMutations