Anyone Have Treatment with 5Fu Monotherapy?

Discussion Board Forums Good News / What’s Working Anyone Have Treatment with 5Fu Monotherapy?

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    Hi Shshaw,

    I also looked around and did not find much additional information for you, but will keep looking.  I am assuming by “pump” you mean the HAI pump a few of the major cancer centers offer, since you had mentioned this in an earlier post.  This is not a very common treatment.  The published studies I have seen for the hepatic arterial infusion (HAI) pump have shown promising results, and because the chemo is delivered directly to the liver, there can be fewer side effects.  5FU (fluorouracil) is a chemo proven to be effective for cholangiocarcinoma, and appears to be one of the chemos used with the HAI pump.

    Some patients have received 5FU in combo with other chemos where the 5FU part is delivered at home through a small infusion device or pump that the patient carries in a pack. This is a different means of delivery than the HAI pump which is surgically implanted.   Some acronyms for 5FU chemo combos used for cholangiocarcinoma with this type of pump are FOLFIRI and FOLFOX.   I believe we have seen reports by patients and caregivers on the boards for these treatment, which could be found using our search engine.

    I hope this is helpful and that your treatment brings good results for you.

    Regards, Mary


    Hi there,

    I did a search on the boards for you using the search forum function and it threw up these discussions here –

    Not a lot to go on there I know. So I did another one for you on just 5FU and it came up with this, much more here.

    I hope that some of that will be of use and interest to you. And I will be keeping my fingers crossed for you as well with regards to the treatment and hope that it works very well indeed.

    My best wishes to you,



    Had 6 cycles of Gem/Cis for intrahepatic non-resectable ICC. A Scan shows main tumor has shrunk, however several small tumors (mets) have grown. Anyone else had results like this? Oncologists now has me on 5Fu monotherapy using pump. Has anyone had this treatment before and what were results?

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