Ascites
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Hi,
I don’t know about the numbness, but most likely you are right that it is from the side effects of the oxaliplatin .With regard to Xeloda, I do feel my legs being tired easily; and I can feel the pain starting coming out from my calf slowly after the 5th cycle, So I asked and got Lovenox for DVT prophylaxis. SOB is another problem but It is not to a point that I cannot take. I do labs every two weeks to a month,so far platelets are in the 170-220 range,the neutrophil are in the 40-50 range. ( low but not too bad) and of course the WBC is a bit lower in the 5 plus range.all the ALT,AST ALK PHOS are in normal range.Albumin is in the 4-4.5 range; the RBC is always on the low side 4.1-4.3 range; HGB is around 14. Bilirubin is between 0.4-0.8 nothing abnormal. BUN/Creatinine is normal at at around 20/1.3 level. When I started the Xeloda, I asked and got the C- reactive protein done as the base line for inflammation and it is within the normal range.
I do CMP,CBC,CA19-9 CEA mg++ ,phosphorus and Lipid profile once a month. If I feel something is different,I will do CBC and CMP q2weeks.
I am on Xeloda and I start my 7th cycle today. So far so good,except dry skin on both feet and a brown ring around the bottom of the 2big toe( the side effected of the XEloda on nails dis coloring and being brittle) Fatigue is a problem and that may be one of the reason I feel SOB after a day’s work in the hospital.
God bless.fatema alzahraa wrote:Hi Jose,
I’m a cardiologist (heart physician) so i’ll try to answer your questions as i can. First of all you should consult her physician because i think there is no correlation between biopsy and ascites so you should make sure it is not an abdominal collection (other than ascites) which may be due to injury during the biopsy.Answer on Q1 yes she can but it should be well investigated, liver disease alone could cause ascites when liver function is disturbed (because one of causes of ascites is decreased albumin “a protein which is synthesized by liver) paracentesis could be performed under certain circumstances and according to its severity, so she should perform the following laboratory investigations (serum total proteins, Serum albumin, prothrombin activity and INR) then she may be recommended to receive human albumin or plasma according to the results.
I should also tell you that any malignancy could cause fluid collection in abdomen, around the heart or around lungs (which called serous cavities) so i told you to consult her physician who could differentiate.
Answer on Q2 ascites in general is not a good sign but don’t worry it could be managed.
I hope i gave you some information which may help you, wish your sister and my mom speed recovery.
Hi Fatema,
Thank you very much for this kind answer. It really helps. I wish the best for your mom.Hughs
JoseHi Percy,
you and everybody here are welcomed, wish i could help.I post a reply under the topic of “radioembolisation my last option” to answer your questions about my mom experience in radioembolisation. Fatigue is increasing she is sleeping most of the time but with body aches which really is bothering her we will have lab investigations next week (her radiologist asked for lab every 2 weeks).
BTW i want to ask you about xeloda when you do your lab while being on it? my mom received oxaliplatin 10 days ago and started xeloda on the next day her oncologist told me to do lab investigations after finishing 14 days of xeloda.
Something more two days ago she told me that she has a sense of heaviness with numbness in both of her legs (from knee to foot), i think that the neuropathic effect of oxaliplatin began to show up when i called her oncologist he told me that we may have to stop it if stopped what will be the other options?? as i read cisplatin has the same side effect and even worse regarding GIT side effects, carboplatin is not highly recommended and i think it is a weak drug.
Hi Jose,
I’m a cardiologist (heart physician) so i’ll try to answer your questions as i can. First of all you should consult her physician because i think there is no correlation between biopsy and ascites so you should make sure it is not an abdominal collection (other than ascites) which may be due to injury during the biopsy.Answer on Q1 yes she can but it should be well investigated, liver disease alone could cause ascites when liver function is disturbed (because one of causes of ascites is decreased albumin “a protein which is synthesized by liver) paracentesis could be performed under certain circumstances and according to its severity, so she should perform the following laboratory investigations (serum total proteins, Serum albumin, prothrombin activity and INR) then she may be recommended to receive human albumin or plasma according to the results.
I should also tell you that any malignancy could cause fluid collection in abdomen, around the heart or around lungs (which called serous cavities) so i told you to consult her physician who could differentiate.
Answer on Q2 ascites in general is not a good sign but don’t worry it could be managed.
I hope i gave you some information which may help you, wish your sister and my mom speed recovery.
Dear friends,
My sister with I-CC stage IV (49 years old) has experimented ascites (swelling in abdomen) just immediately after the biopsy. This symptom is the most annoying problem she has had, even worse than any side effect from quemo (already two cycles). I know there is a system to extract this liquid from the abdomen (paracentesis) which has been applied to her once. I have two questions:
1) Could a patient live with this symptom and being alleviated periodically with paracentesis from time to time without any further damage to her health?
2) Is this symptom a sign of worsening up to the point that we should expect an acceleration of her illness?If any of you have had this symptom I would appreciate any information. Thank you very much
All the best
Jose
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