Side affects reported with treatment of Opdivio (nivolumab)

Immune checkpoint inhibitors can cause side effects. Report all symptoms to your healthcare team.

1. Patients will be monitored for Immune-Medicated Rash. Severe rash (including rare cases of fatal toxic epidermal necrolysis) occurred in the clinical program of Opdivo.

Symptoms are:
Rash
Itchiness of the skin
Skin blisters
Ulcers in mouth or other mucus membranes

2. Immune-Medicated Encephalitis can occur with Opdivo treatment

Symptoms are:
Headache
Fever
Tiredness or weakness
Confusion
Memory problems
Sleepiness
Hallucinations
Seizures
Stiff neck

Reference: Immune-Mediated Adverse Reactions Management Guide

Bristol-Mayers Squibb