Discussion Board Forums Adverse Reactions & Side Effects Side affects reported with treatment of Opdivio (nivolumab)

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    Immune checkpoint inhibitors can cause side effects. Report all symptoms to your healthcare team.

    1. Patients will be monitored for Immune-Medicated Rash. Severe rash (including rare cases of fatal toxic epidermal necrolysis) occurred in the clinical program of Opdivo.

    Symptoms are:
    Rash
    Itchiness of the skin
    Skin blisters
    Ulcers in mouth or other mucus membranes

    2. Immune-Medicated Encephalitis can occur with Opdivo treatment

    Symptoms are:
    Headache
    Fever
    Tiredness or weakness
    Confusion
    Memory problems
    Sleepiness
    Hallucinations
    Seizures
    Stiff neck

    Reference: Immune-Mediated Adverse Reactions Management Guide

    Bristol-Mayers Squibb

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