2 years clear and its back!

Hi,
You wrote:
“One more question has anyone had surgery after a resection to remove a lesion? I had the right side of my liver removed but I’m working with a full otherwise healthy liver except for the lesion.”

Yes, I had 2 liver resections within 2 years.(is that what you mean about the lesion?)
what lesion and may I ask how big it is;why cannot use RFA to ablate the lesion by the interventional radiologist if it is under 3cm? It the lesion too close to major organs ,artery or veins? The reason is simple, it is much easier to take than the chemotherapy you mention.and if it is not contraindicated,most of the time you will have little or no side effect.
The only thing I would consider chemotherapy first is if your primary diagnosis 24 months ago is extrahepatic or Hilar CCA instead of intrahepatic.

Below are some(not all) information for ABRAXANE( a protein-bound paclitaxel.belong to the TAXOL family—from drug manufacture web site.

Patients who have a severe allergic reaction to ABRAXANE should not take the drug again
If you have a very low white blood cell count, you should not take ABRAXANE. If your white blood cell count goes down while taking ABRAXANE, you should stop taking it until your white blood cell count returns to normal. If your white blood cell count drops very low, your doctor will lower your dose of ABRAXANE
People treated with ABRAXANE often have a side effect called sensory neuropathy, a numbness, tingling, or burning in the hands, feet, and ankles. If you get mild sensory neuropathy, you will probably not have to lower your dose of ABRAXANE. If sensory neuropathy becomes severe, you may have to stop taking ABRAXANE until it improves, and then continue treatment at a lower dose
Treatment with ABRAXANE can make liver problems worse. If you have liver problems, your starting dose of ABRAXANE should be lowered
ABRAXANE contains albumin (human), a derivative of human blood
If you are pregnant, or plan to become pregnant, ABRAXANE can harm your unborn baby. Women who may become pregnant should use effective birth control (contraception). Talk to your doctor about the best way to prevent pregnancy while receiving ABRAXANE
Because it is not known if ABRAXANE passes into your breast milk, you and your doctor should decide if you will receive ABRAXANE or breastfeed
Men should not father a child during treatment with ABRAXANE. ABRAXANE can harm the unborn baby of your partner
In a clinical trial, severe heart and blood vessel side effects occurred in approximately 3% of patients taking ABRAXANE. Side effects included chest pain, heart attack, fluid under the skin, blood clots in the veins or lungs, and high blood pressure. Stroke and heart failure were reported
The most common side effects of ABRAXANE included:
Hair loss
Numbness or tingling in the hands or feet
Abnormal heartbeat
Tiredness
Joint and muscle pain
Changes in your liver function tests
Low red blood cell count (anemia). Tell your doctor if you feel weak, tired or short of breath
Nausea
Infections. If you have a fever (temperature of greater than 100.4º F) or other signs of infection, tell your doctor right away
Diarrhea
Other side effects included vision problems, kidney problems, fluid retention, liver problems, and allergic reactions, and a decrease in blood clotting cells (platelets). Dehydration and fever have also been reported
Treatment with ABRAXANE can cause irritation where the medicine is injected (injection site reactions). When taking ABRAXANE, you should be monitored by your doctor or nurse to make sure no problems occur at the injection site
It is not known whether ABRAXANE interacts with other drugs, so be sure to tell your doctor about any medicines you are taking
ABRAXANE has not been studied in children or in people with kidney problems

Please see full Prescribing Information, including Boxed WARNING, CONTRAINDICATIONS, WARNINGS AND PRECAUTIONS, and ADVERSE REACTIONS.
God bless.

Kris: So sorry to hear about the ‘lesion’ on your liver. My husband Tom had lesions and his oncologist was not worried at all about the lesions because they were not tumors.

Tom was on Xleoda, pill form and tolerated it very well. He never had any reactions to it. After that he was on Gemzar and Cisplatin and also tolerated that very well. It wasn’t until he started on 5-FU that he experienced any reaction and that could be because he was already so worn down from the cancer itself and all the other issues he was dealing with, along with a large weight loss.

The radiation treatments actually were worse for him then the chemo.

He never ‘lost’ his hair, it only thinned out a bit. I thought it was rather funny that all he was worried about was loosing his hair from the chemo. I never realized that he was so vain and he said “I spent 63 years growing this hair and I’m kinda partial to it”….

Hope all goes well with your treatment and that you tolerate it as well as my Tom did.

Hugs,
Margaret