fatema-alzahraa
Forum Replies Created
-
Posts
-
HIi Racheal,
My dear mom had met to her right ovary discovered by increased uptake by PET-Ct and confirmed by CT scan.Hi,
Mom is using a drug named Em-Ex (Granisetron Hydrochloride) which worked for her in previous cycles, i hope it will have the same effect now with her persistent nausea and vomiting, she is not doing well as i told you about her CT results but her labs are going worse her bilirubin increased (total 2.5, direct 1.5) her abdominal distention increased (now she has moderate ascites), she has severe back pain (related to her right side) also she lost her appetite.She started chemo yesterday (GEMOX) with modified dose of Gemzar, i asked her oncologist to add Tarceva but he thinks it is not a good idea (due to its results in trials) so finally we decided to postpone it till following her bilirubin level with chemo.
Something more her hepatologist asked for MRCP to detect is it obstructive jaundice or not? and if she will be a candidate for stenting?
Hi Percy,
Really, i’m so grateful for your reply and care,thank you very much.Today i went to chest doctor, when he saw CT (done with PET) he told me that basal patches are neither pneumonia nor TB but it is radiation pneumonitis and he said YES it causes fever and dry cough he prescribed corticosteroids (ofcourse under umbrella of antibiotic) i’m really surprised her lung uptake was 16% and the interventional radiologist told me that is ok and we can proceed!!! i’m afraid that it could deteriorate.
Hi Percy,
Why are you on it? as i got from internet it is for hepatitis B and it is different fro acyclovir.Hi,
My mom had Y90 radioembolization for her right lobe on 22nd February, her CA19.9 after 4 weeks is increased (actually it has been increasing since the beginning of treatment her baseline was 183 then 540 after 3 cycles of GEMOX and still rising even after radioemb.) but what is really weird her AFP which is declining after chemo and radioemb., when i asked her oncologist he told me that CA19.9 is affected by many conditions (e.g. cholangitis which me be caused by radiation may raise it) her radiologist told me that he thinks that she has cholangio-hepatoma due to high AFP.Hi,
No you should restrict salt to avoid water retention and also restrict proteins (specially red meat) to avoid increase of ammonia in her blood (which causes hallucination “encephalopathy”) and give her fish meat instead till consulting her treating physician.If you need to ask about anything you are welcomed.
Hi Jose,
As i remember you had a post asking about ascites, did you check your sister’s liver function?? if not you should do that. really i don’t want to scare you but “odd”” ideas and being talkative may reflect disturbed liver function and may be grade of hepatic encephalopathy, please don’t explain every symptom to be a side effect of chemotherapy.Another thing take care while using anxiolytics and SEDATIVES (Diazepam compounds), they are metabolised by liver so in liver illness they may be harmful.
Sorry if i made you worried but i should warn you, wish her and my mom spedd and soon recovery.
Please keep us updated.
Hi Ed,
Wish you good luck in your radioembolization, if you please i want to ask you some questions if you don’t mind.as i read you are on a clinical trial (GEMOX+Panitumumab), what do you mean by 18 cycles do you mean weeks?? my mother was on GEMOX (3cycles), cetuximab 12 weeks , Xelox(xeloda+oxaliplatin) two cycles and i think that we will have to stop oxaliplatin due to neuropathy too.
So what did your radiologist tell you about the duration you should be off gemzar? i’m really confused as my mom now is on xeloda (she hed her 1st embolization on 22nd february and planned for the next one on 10th April) her radiologist told me that it will be enough to stop xeloda (capecitabine) 10 days before embolisation!! and if you stopped oxaliplatin what are their suggestion about alternatives?BTW also my mom has large mass in her right lobe and multiple (countless in the other).
Thanks alot and keep in touch.
Hi Percy,
you and everybody here are welcomed, wish i could help.I post a reply under the topic of “radioembolisation my last option” to answer your questions about my mom experience in radioembolisation. Fatigue is increasing she is sleeping most of the time but with body aches which really is bothering her we will have lab investigations next week (her radiologist asked for lab every 2 weeks).
BTW i want to ask you about xeloda when you do your lab while being on it? my mom received oxaliplatin 10 days ago and started xeloda on the next day her oncologist told me to do lab investigations after finishing 14 days of xeloda.
Something more two days ago she told me that she has a sense of heaviness with numbness in both of her legs (from knee to foot), i think that the neuropathic effect of oxaliplatin began to show up when i called her oncologist he told me that we may have to stop it if stopped what will be the other options?? as i read cisplatin has the same side effect and even worse regarding GIT side effects, carboplatin is not highly recommended and i think it is a weak drug.
Hi Jose,
I’m a cardiologist (heart physician) so i’ll try to answer your questions as i can. First of all you should consult her physician because i think there is no correlation between biopsy and ascites so you should make sure it is not an abdominal collection (other than ascites) which may be due to injury during the biopsy.Answer on Q1 yes she can but it should be well investigated, liver disease alone could cause ascites when liver function is disturbed (because one of causes of ascites is decreased albumin “a protein which is synthesized by liver) paracentesis could be performed under certain circumstances and according to its severity, so she should perform the following laboratory investigations (serum total proteins, Serum albumin, prothrombin activity and INR) then she may be recommended to receive human albumin or plasma according to the results.
I should also tell you that any malignancy could cause fluid collection in abdomen, around the heart or around lungs (which called serous cavities) so i told you to consult her physician who could differentiate.
Answer on Q2 ascites in general is not a good sign but don’t worry it could be managed.
I hope i gave you some information which may help you, wish your sister and my mom speed recovery.
Hi,
Yes i think there is contradiction between both of them and i discussed that with her oncologist who was surprised and decided to complete xeloda for this cycle and give her oxaliplatin in the next cycle and no xeloda till 10/4/2012 (time of next radioembolization if she is stable).My mom finished Erbitux today (12th week) and the doctor said it is enough.
Regarding side effects yes it is fatigue the major problem and FEVER which really scared me two days ago when she had shivering she is still feverish till today. Also she has some abdominal pain. we are still waiting for her next lab investigations to decide the final time of her next embolization.
Hi Percy,
Sorry but i think i didn’t get what you meant, do you mean that 10-14 days are enough to stop xeloda before radioembolisation?, i read an article about sirspheres (the type used for my mom) where they said that capecitapine is a contraindication for radioemb. if used less than 2 months before procedure or planned to be used in the future!!I found during browsing the internet that here is a phase I trial in cases with intrhepatic CC to calculate the dose of Y90 combined with capecitapine and their suggestion was to get use of the sensitizing effect of capecitapine on tumor cells for better response for Y90.
Hi,
My mom had radioembolisation for her right lobe on 22nd february, she has fever since two days and today her temp is 38 celsius with chills i’m really so worried, her doctor said that it is expected.another thing she is now on xeloda (capecitapine) her treating physician said that we should only stop it 10 days before injection of her left lobe!! but what i got from the web that it should be stopped 2 months before the procedure and shouldn’t be used again!! please i need you experience i’m really so worried.
