Hi vtkb, thank you for your response and great question. Yes, we did ask the oncologist why Folfox because our research led us to expect GemCis as well. It is because the pathology report from the liver biopsy leaves open the possibility of a primary tumor elsewhere, so for now we are treating this as a cancer of unknown origin, and the Folfox would cover the other possible primary cancers. If we determine that the CCA is the primary, then we can change the treatment accordingly.