gavin
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gavin
ModeratorNever too late Kathi!!
October 27, 2015 at 10:42 pm in reply to: Agios to Present Clinical Data from Ongoing AG-120 Phase 1 Trial #90178gavin
ModeratorHi Jason,
Thanks for that and great to see you on here again. 25% up in one day. Like you, I would be guessing that some got wind of the trial results to move up that much in one day. The IBB was up 3.25% today so it was a strong day anyway for the sector but 25%, someone must have heard something I would argue.
ArQule also releasing some info and trial details on the 7th November –
“About FGFR and ARQ 087
ARQ 087 is a multi-kinase inhibitor designed to preferentially inhibit the fibroblast growth factor receptor (“FGFR”) family with demonstrated efficacy in FGFR2 amplified tumors. The FGFR pathway is disrupted in several ways in human cancer, thus providing numerous therapeutic targets for an inhibitor of this pathway. ARQ 087 has demonstrated inhibition of tumor growth and downstream signaling in vivo in tumors whose growth is driven by these targets.
Signals of single agent activity with this compound were observed in Phase 1a testing. Phase 1b expansion cohorts with ARQ 087 include patients with cholangiocarcinoma and adrenocortical tumors, as well as those with FGFR translocations, amplification and mutations. Clinical development of ARQ 087 has advanced into Phase 2 for intrahepatic cholangiocarcinoma (“iCCA”) following the observation of two confirmed partial responses in this patient population in the Phase 1 portion of the program.
Fingers crossed for good news from both camps!
Gavin
gavin
ModeratorHi Rosalie,
Welcome to the site. Sorry that you had to find us all here but glad that you have joined as you are so in the best place for support and help and will get so much of each from everyone here. Yes it can be hard to accurately diagnosis someone with CC and for many it does take time unfortunately. In my dads case it took over 3 week for the full diagnosis to come through and they had to rule out gall stones and gall cancer before they came up with his diagnosis of CC.
But I am glad that you are seeing docs at the Cleveland Clinic and am sure that you will be in very good hands there. We do have some members that have been diagosed and treated there and hope that they will be along soon to share their experiences of the Cleveland Clinic with you. I think Lisa was treated there.
Please keep on coming back here and know that we are here for you as well. I know you will learn more at your meeting on the 2nd and please let us know how that goes.
My best to you,
Gavin
gavin
ModeratorSuperb news Melinda, love it!!!
Huge celebratory hug for you!
Gavin
gavin
ModeratorShe must love you loads then!!!
gavin
ModeratorThanks for that Genevieve and like Lainy says, 4 years is nothing to be scoffed at indeed. He has been through so much with everything hasn’t he and I keep everything crossed for the RFA to do it’s job and send this thing packing once again!
My best to you and your husband,
Gavin
October 25, 2015 at 1:57 pm in reply to: Latest advances in the pathological understanding of cholangiocarcinom #90163gavin
ModeratorIndeed Marion. But we could so do with the puzzle being much smaller and easier to solve as well!
Hugs,
Gavin
October 24, 2015 at 12:12 pm in reply to: Carcinogenic Parasite Secretes Growth Factor That Accelerates Wound He #90127gavin
ModeratorCancer-causing worm could help heal chronic wounds, researchers find
gavin
ModeratorThanks loads for that Derin!!
gavin
ModeratorHi Matt,
Will so join in with the keeping things crossed for you with the Keytruda and am sending loads of positive vibes your way as well. Love your pics in the other thread as well and looking forward to hearing from you in the good news section of the site!
My best to you,
Gavin
gavin
ModeratorCathy,
Real sorry to hear this news from you, real sorry indeed. I so know that this will have hit you like a ton of bricks, again. You are indeed a fighter as everyone else has said to you and I know that you will get the boxing gloves on again to take this on. I so hope that you get some good news at the meeting today and that your team have a plan ready to get to work on dealing with this.
You know we are here for you.
Hugs,
Gavin
gavin
ModeratorHi Kernos,
The stable and shrinkage are good and I would certainly focus on that right now. It could well be the case as Catherine says that the 15mm one was missed first time around and that it is not actually new. Hopefully you will find out more about that when you meet the onc and also what they are planning to do about this treatment wise. Please let us know how everything goes and know that we are here for you.
My best wishes to you,
Gavin
gavin
ModeratorHi Daisy,
Wish that I could help with the testing results but I can’t I’m afraid and would net even like to take a stab at them to be honest.
7 Miles, wow! We would all struggle to keep up with your mum I would think!! Yes she certainly is doing great and I hope that the scans go well and please remember to let us know how that goes as well.
My best to you and your mum,
Gavin
October 17, 2015 at 6:41 pm in reply to: Eating Hints Before, During, and After Cancer Treatment #90067gavin
ModeratorMacmillian in the Uk has loads of stuff as well about nutrition etc, links here worth a look as well as the one Marion has provided.
http://www.macmillan.org.uk/information-and-support/coping/side-effects-and-symptoms/eating-problems
Recipes! Recipes always make me
http://www.macmillan.org.uk/information-and-support/coping/maintaining-a-healthy-lifestyle/recipes
Gavin
gavin
ModeratorMSKCC has a great database for searching about various herbs, properties and claims etc. Well worth a look/search if someone is interested in something and can be found here –
https://www.mskcc.org/cancer-care/treatments/symptom-management/integrative-medicine/herbs/search
Gavin
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