“We enjoy the shade of a mighty oak tree because someone before us planted it.”
What is the Genome-Wide Association Study (GWAS)?
- A study of genetic variations associated with a specific disease like cholangiocarcinoma
- Involves two groups of participants: people with, and people without, the disease
- DNA from a small sample of blood is obtained from each participant
- Results help researchers to develop better strategies for prevention, screening, diagnosis and treatment
Our goal is to have 2,500 volunteers participate in the Genome-Wide Association Study (GWAS).
Your participation will help scientists to:
- Inspire progress and find new ways to prevent, detect, diagnose, and treat cholangiocarcinoma
- Discover important genetic risk factors for cholangiocarcinoma that may affect your family
Who can participate?
- Patients, caregivers, family, friends, co-workers, neighbors – men and women of any age
- You do NOT need to know someone with cholangiocarcinoma . . . we are looking for ALL volunteers!
How will you participate?
- Fill out a consent form and questionnaire
- Give a sample of blood
- Submit your Contact Information Form now. The Study Coordinator will follow-up within a few days.
- After you Submit your Contact Information Form, a Study Coordinator will contact you within a few days
- A kit with instructions will be mailed to you
- There is no charge to participate – any costs for drawing the blood will be reimbursed
- The blood sample can be drawn by your family doctor or anywhere in your community; you do not need to go to the Mayo Clinic or any of the other participating institutions
- GWAS participants are not required to provide urine or stool samples or any future blood samples
- Original signatures are required on the Consent Form (only pages 10, 11 & 13 need to be mailed back to the Study Coordinator)
- We will be very happy to answer ALL of your questions:
Mikayla Schmidt: Schmidt.Mikayla2@mayo.edu
Dr. Fowsiyo Ahmed: Ahmed.Fowsiyo@mayo.edu
- There is a critical need for cholangiocarcinoma research.
- Dear Cholangiocarcinoma Foundation Patient Community, I write today to ask for your help. Although this is thought to be a rare disease, cases of cholangiocarcinoma are rising in the US and worldwide. Scientists do not know what causes cholangiocarcinoma or how it can be treated effectively.
- Researchers are trying to find individuals who might have a high risk for developing cholangiocarcinoma so they can identify new ways to detect, diagnose, and treat it. Mayo Clinic is one of many institutions participating in a Genome-Wide Association Study (GWAS) for cholangiocarcinoma. We compare DNA from small samples of blood from two groups: people with the disease (you) and people without (your family members or friends).
- This helps us to identify important genetic risk factors for cholangiocarcinoma.
- There is no cost to you and it is easy to participate by donating a small sample of blood and completing a medical history questionnaire.
- Lewis R. Roberts, M.B. Ch.B., Ph.D Mayo Clinic, Division of Gastroenterology and Hepatology
- Submit your Contact Information Form now.
- The Study Coordinator will follow up within a few days.
- Mayo Clinic Rochester (USA)
Dr. Lewis Roberts
- Oncóloga Médico-Instituto Nacional del Cáncer (Chile)
Dr. med. Bettinna Muller
- University of Manchester (U.K.)
Dr. Juan Valle
- The University of Hong Kong, Hong Kong, China
Dr. Thomas Yau
- Alberta Health Services (Canada)
Dr. Oliver Bathe
- University Mainz, University Medical Center of the Johannes Gutenberg (Germany)
Dr. Peter Galle and Dr. Arndt Weinmann
- Mayo Clinic Arizona (USA)
Dr. Mitesh Borad
- Universitätsklinikum des Saarlandes
Dr. Vincent Zimmer and Frank Lammert
- Massachusetts General Hospital
Dr. Andrew Zhu and Dr. Nabeel Bardeesy
- Imperial College (UK)
Dr. Shahid Khan
- Biodonostia Research Institute (Spain)
Dr. Jesus Banales
- University Health Network, Toronto, Canada
Dr. Sean Cleary
- Johns Hopkins, Baltimore, Maryland
Dr. Stephen Meltzer and Dr. Florin Selaru
- Mayo Clinic Florida (USA)
Dr. Tushar Patel
- MD Anderson Cancer Center (USA)
Dr. Manal Hassan
- University of California, San Francisco (USA)
Dr. Kate Kelly
- National Cancer Institute
Dr. Jill E. Koshiol
- Baylor College of Medicine
Dr. Prasun Kumar Jalal
- Harvard Cancer Center
Dr. Rebecca Miksad
- Mayo Clinic, Rochester, MN (Cancer Center and Pancreatic Cancer Research)
Dr. Gloria M. Petersen
- Liver Associates of Texas
- University of Rochester in Rochester, New York
Dr. Aram Hezel
- Karolinska Institutet at Karolinska University Hospital, Huddinge
Dr. Bengt Isaksson and Dr. Weimin Ye
- University of Puerto Rico, School of Medicine
Jose Rivera Esther A. Torres Dr. Irene Villami
- Loyola Medicine
Dr. Steve Scaglione
- University of Virginia
Dr. Osama Rahma
- University of San Diego, CA (UCSD)
Robert Gish Yuko Kono