Research Grants

Since 2015, the Foundation has awarded 49 Research Fellowships totaling $2,460,000 in seed-funding to raise awareness about cholangiocarcinoma and inspire innovative, high-quality research

The Cholangiocarcinoma Foundation Research Fellowship Program is aimed at supporting early-career researchers focusing on studies in cholangiocarcinoma.

2023 Research Fellowship Awards

Tomlinson, Jennifer

Andrea Lynn Scott Memorial Research Fellowship

Supported by Jason Scott & family in memory of Andrea Scott

Jennifer Tomlinson, Mayo Clinic
The Role of YAP in Cholangiocarcinoma Tumor Immunity

In memory of Andrea Scott, Jason Scott, family, and friends are supporting the Andrea Lynn Scott Memorial Research Fellowship grant. The grant is being awarded to Jennifer Tomlinson from Mayo Clinic. Jennifer will be investigating the Role of YAP in Cholangiocarcinoma Tumor Immunity.

"I am incredibly thankful to have been given the opportunity to further my scientific exploration of cholangiocarcinoma oncogenesis and biochemical signaling. Through the Andrea Scott Memorial fellowship, I hope to make meaningful scientific progress that will one day improve the lives of patients with this disease."

Nebbia, Martina2

AstraZeneca/CCF Research Fellowship

Supported by AstraZeneca

Martina Nebbia, Cedars-Sinai Medical Center
A safety switch for safe clinical application of tumor antigen-specific CAR -T cell immunotherapy in multi-focal and metastatic intrahepatic cholangiocarcinoma.

Supported by AstraZeneca, the AstraZeneca/CCF Research Fellowship grant, is being awarded to Martina Nebbia from Massachusetts General Hospital. Martina will be investigating a safety switch for safe clinical application of tumor antigen-specific CAR -T cell immunotherapy in multi-focal and metastatic intrahepatic cholangiocarcinoma.

"We strongly believe that the novel strategy based on tumor antigen-specific CAR -T cell immunotherapy will have a major impact on the treatment of cholangiocarcinoma, and the results generated from this project will provide the background to translate our strategy into a clinical setting to treat patients with multi-focal or metastatic disease.

As a young investigator, it’s a huge honor for me to have been selected for the AstraZeneca/CCF Research Fellowship. I’m grateful to AstraZeneca for supporting this project and believing in our research and to CCF to make all of this possible."

Tang, Tin-Yun

Bruce Coppock Memorial Research Fellowship

Supported by CCF Board and Staff - In memory of Bruce Coppock to honor his years of service

Tin-Yun Tang, The University of Texas MD Anderson Cancer Center
MTAP Loss Clonality and Targeting in Cholangiocarcinoma

In memory of Bruce Coppock, who passed away from the disease in December, the CCF board and staff are supporting the Bruce Coppock Memorial Research Fellowship grant, to recognize and honor Bruce’s years of service. The grant is being awarded to Tin-Yun Tang from The University of Texas MD Anderson Cancer Center. Tin-Yun will be investigating MTAP Loss Clonality and Targeting in Cholangiocarcinoma.

Xia, Jonathan

Jacques Dupont Memorial Research Fellowship

Supported by Barbara Dupont, her family and friends in memory of Jacques Dupont

Jonathan Xia, McGaw Medical Center of Northwestern University
Integrating Multi-omics in Bile for Biomarker Discovery in Primary Sclerosing Cholangitis and Cholangiocarcinoma

In memory of Jacques Dupont, Barbara Dupont, family, and friends are supporting the Jacques Dupont Memorial Research Fellowship grant. The grant is being awarded to Jonathan Xia from McGaw Medical Center of Northwestern University. Jonathan will be investigating the integration of Multi-omics in Bile for Biomarker Discovery in Primary Sclerosing Cholangitis and Cholangiocarcinoma.

Green, Benjamin

Kathleen & Paul Sidenblad Research Fellowship

Supported by Kathleen and Paul Sidenblad

Benjamin Green, University of Hawaii Cancer Center
A peptide vaccine targeting WT1 for immunotherapy against intrahepatic cholangiocarcinoma

Supported by Kathleen and Paul Sidenblad, the Kathleen and Paul Sidenblad research fellowship grant is being awarded to Benjamin Green from University of Hawaii Cancer Center. Benjamin will be investigating a peptide vaccine targeting WT1 for immunotherapy against intrahepatic cholangiocarcinoma.

"I strongly believe in the potential of peptide vaccines to become an important treatment in the fight against cholangiocarcinoma. As a new investigator who has treated cholangiocarcinoma first-hand, it means so much to receive support from a fellowship through this patient-driven organization. Thank you, Kathleen and Paul Sidenblad and CCF, for believing in me and our team's research."

Dr. Ethan Ludmir

Marion U. Schwartz Memorial Research Fellowship

Supported by CCF in memory of Marion U. Schwartz

Ethan Ludmir, The University of Texas MD Anderson Cancer Center
Integrating Radiomics and Immunogenomics to Predict Tumor-Related Liver Failure for Patients with Metastatic Intrahepatic Cholangiocarcinoma

In memory of Marion U. Schwartz, CCF is supporting the Marion U. Schwartz Memorial Research Fellowship grant. The grant is being awarded to Ethan Ludmir from The University of Texas MD Anderson Cancer Center. Ethan will be investigating the integration of Radiomics and Immunogenomics to Predict Tumor-Related Liver Failure for Patients with Metastatic Intrahepatic Cholangiocarcinoma.

"As we gain deeper understanding into the optimal treatment of cholangiocarcinoma, we are learning more and more how much of a "team mentality" can help our patients.  The support of the Marion U. Schwartz Memorial Research Fellowship is deeply meaningful for me as a young oncologist with a specialization in the treatment of biliary tract cancers.  Through these efforts, CCF deepens the partnership between oncologists and the patient community, allowing us together to focus on meaningful patient-centered advances in the treatment of cholangiocarcinoma."

Zhen, Yuanli

Mark R. Clements Memorial Research Fellowship

Supported by CCF in memory of the Cholangiocarcinoma Foundation's Co-Founder, Mark Clements

Yuanli Zhen, Massachusetts General Hospital
Mobilization of anti-tumor immunity in FGFR2-driven cholangiocarcinoma

In memory of the Cholangiocarcinoma’s Co-founder, Mark R. Clements, who passed away from the disease in 2007, CCF is supporting the Mark R. Clements Memorial Research Fellowship grant. The grant is being awarded to Yuanli Zhen from Massachusetts General Hospital. Yuanli will be investigating the mobilization of anti-tumor immunity in FGFR2-driven cholangiocarcinoma.

Olaizola, Paula

The Quack Out Cholangio 5k Research Fellowship Grant

The Quack Out Cholangio 5k Research Fellowship Grant honors Kathy Byrnes (known as Kathy Kbt) and Shannon McCarty

Paula Olaizola, MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine
Understanding of the reciprocal interactions between cancer cells and CAFs within the emerging cholangiocarcinoma tumour microenvironment

The Quack Out Cholangio 5k Research Fellowship Grant honoring Kathy Byrnes (known as Kathy Kbt) and Shannon McCarty is awarded to Paula Olaizola from MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine. Paula will be investigating the reciprocal interactions between cancer cells and CAFs within the emerging cholangiocarcinoma tumour microenvironment. In their memory, Kathy's husband, Billy, and Shannon's husband, Ron, were the official starters of the 3rd Annual Quack Out 5k in 2022. Shannon, a mother of 3, was diagnosed with stage 4 intrahepatic cholangiocarcinoma at age 44 and passed away at age 46.  Shannon loved traveling, the Denver Broncos, and eating terrible things like scrapple. Kathy was diagnosed with stage 4a intrahepatic cholangiocarcinoma at age 36 and passed away at age 41. Kathy loved traveling, napping, and spending time with her friends and family.

"I am very grateful to the Cholangiocarcinoma Foundation, the donors, and Dr. Luke Boulter for supporting my personal and scientific growth. This is a great opportunity to better understand CCA pathogenesis to find novel therapeutic approaches to improve the welfare and outcome of patients."

Warren, Emilie

Stewart Mather Memorial Research Fellowship

Supported by Colleen Mather and the Mather Family Foundation in memory of Stewart Mather

Emilie Warren, Emory University
CD4+CD26+ tumor-infiltrating lymphocytes represent a novel strategy to improve the efficacy of adoptive T cell transfer therapy in cholangiocarcinoma

In memory of Stewart Mather, who passed away from the disease in 2020, his wife Colleen and the Mather Family Foundation are supporting the Stewart Mather Memorial Research Fellowship grant. The grant is being awarded to Emilie Warren from Emory University. Emelie will be investigating how CD4+CD26+ tumor-infiltrating lymphocytes represent a novel strategy to improve the efficacy of adoptive T cell transfer therapy in cholangiocarcinoma.

Conboy, Caitlin

Susan Morrison Research Fellowship

Supported by Susan G. Morrison

Caitlin Conboy, Mayo Clinic
Targeting Epigenetic Dysregulation in Cholangiocarcinoma

Supported by Susan G. Morrison, the Susan Morrison research fellowship grant is being awarded to Caitlin Conboy from Mayo Clinic. Caitlin will be targeting Epigenetic Dysregulation in Cholangiocarcinoma.

2022 Research Fellowship Awards

Marina Barcena-Varela

Andrea Lynn Scott Memorial Research Fellowship

Supported by Jason Scott & family in memory of Andrea Scott

Marina Barcena-Varela
Icahn School of Medicine at Mount Sinai

Harnessing the microbiome for precision cholangiocarcinoma Immunotherapy

Srinadh Choppara

Supriya “Shoop” Saha Memorial Research Fellowship

Supported by CCF, colleagues, friends, and family in memory of Supriya Saha, MD

Srinadh Choppara
University of Michigan

Targeting mitochondrial metabolism to sensitize chemoresistant cholangiocarcinoma tumors

Michael Lidsky

Margaret M. Brown Memorial Research Fellowship

Supported by Janice and Dean Meyer – in honor of her mother who passed away from CCA

Michael Lidsky
Duke University

Improving therapeutic efficacy and durability in FGFR2
fusion positive cholangiocarcinoma

Cecilia Monge

Marion U. Schwartz Memorial Research Fellowship

Supported by CCF in memory of Marion U. Schwartz

Cecilia Monge
NIH/National Cancer Institute

A phase II trial of Pembrolizumab and CDX-1140 in combination with CAPOX (capecitabine/oxaliplatin) in patients withadvanced biliary tract cancer

Evan O'Loughlin

Mark R. Clements Memorial Research Fellowship

Supported by CCF in memory of Mark R. Clements

Evan O’Loughlin
Massachusetts General Hospital Cancer Center / Harvard Medical School

Modeling FGFR-driven biliary tumorigenesis & therapeutic response in 3D

Jutarop Phetcharaburanin

Sarah Bennett Memorial Research Fellowship

Supported by CCF in memory of Sarah Bennett

Jutarop Phetcharaburanin
Khon Kaen University, Thailand

Targeted serum metabolomics for identification of panel bile acid marker-specific O. viverrini infection, liver morbidity and cholangiocarcinoma

Rutger Jan-Swijnenburg

Jacques Dupont Memorial Research Fellowship

Supported by Barbara Dupont, family & friends in memory of Jacques Dupont

Rutger-Jan Swijnenburg
Amsterdam UMC, Netherlands

Clinical Translation of Integrin αvβ6-targeted molecular imaging for cholangiocarcinoma
detection - MIMIC

Alessandro Gambella

Kathleen & Paul Sidenblad Research Fellowship

Supported by Kathleen and Paul Sidenblad

Alessandro Gambella
UPMC Montefiore

Precision pathology in cholangiocarcinoma: the role of immune synapses and vascular framework in patient management

Kishor Pant

Kathleen & Paul Sidenblad Research Fellowship

Supported by Kathleen and Paul Sidenblad

Kishor Pant
Regents of the University of Minnesota

The role of primary cilia in EGFR signaling regulation in cholangiocarcinoma

Vindhya Vijay

Kathleen & Paul Sidenblad Research Fellowship

Supported by Kathleen and Paul Sidenblad

Vindhya Vijay
Massachusetts General Hospital Cancer Center / Harvard Medical School

Understanding the role of loss-of-function BAP1 mutations in pathogenesis of cholangiocarcinoma

Daniel Zabransky

Kathleen & Paul Sidenblad Research Fellowship

Supported by Kathleen and Paul Sidenblad

Daniel Zabransky
Johns Hopkins School of Medicine

D-2-HG as a modulator of fibroblasts and antitumor immunity in the IDH1-mutant cholangiocarcinoma tumor microenvironment

2021 Research Fellowship Awards

Alexander Baker

QED Therapeutics/CCF Research Fellowship

Supported by QED Therapeutics, a Bridgebio Company

Alexander Baker, PhD
Mayo Clinic

Precision oncolytic virotherapy targeted to FGFR2-IIIb as a multi-modal therapy to induce cholangiocarcinoma tumor cell killing  

Christopher Chen, MD

Andrea Lynn Scott Memorial Research Fellowship

Supported by Jason Scott & family in memory of Andrea Scott

Christopher Chen, MD
Stanford University

Clonal origins of metastatic cholangiocarcinoma

Bridget Keenan, MD, PhD

Supriya "Shoop" Saha Memorial Research Fellowship

Supported by Agios Pharmaceuticals, colleagues, friends, and family in memory of Supriya Saha, MD

Bridget Keenan, MD, PhD
University of California San Francisco

Deciphering the role of cancer-associated myeloid cells in resistance to immunotherapy in biliary cancer

Miguel Ángel Martin, PhD

Margaret M. Brown Memorial Research Fellowship

Supported by Janice (current patient) and Dean Meyer – in honor of her mother who also died from CCA

Miguel Ángel Martin, PhD
Icahn School of Medicine at Mount Sinai

Investigating the role of YAP1 signaling in shaping the tumor immune landscape of intrahepatic cholangiocarcinoma

Qibiao Wu, PhD

Marion U. Schwartz Memorial Research Fellowship

Supported by CCF in memory of Marion U. Schwartz

Qibiao Wu, PhD
Harvard University

Explore signaling pathways and combination therapy in FGFR2-activated cholangiocarcinoma

Mark Yarchoan, MD

Mark R. Clements Memorial Research Fellowship

Supported by CCF in memory of Mark R. Clements

Mark Yarchoan, MD
Johns Hopkins Medicine

Deep immune profiling of intrahepatic cholangiocarcinoma with CODEX multiplexed imaging