Call for Letters of Intent

The Cholangiocarcinoma Foundation (CCF) is a non-profit organization founded in 2006 to find a cure and improve the quality of life for those affected by cholangiocarcinoma (bile duct cancer).

Cholangiocarcinoma Foundation Research Fellowship Program

In 2015, the Cholangiocarcinoma Foundation established a Research Fellowship Program aimed at supporting early-career researchers worldwide focusing on the study of cholangiocarcinoma. To date, nearly $1,500,000 has been awarded to raise awareness about cholangiocarcinoma and inspire innovative, quality research. 

The Cholangiocarcinoma Foundation chooses grant recipients carefully to ensure that they will build working relationships between researchers, institutions, and industry and share information, samples, and expertise with others in the field. Prior experience in the field of cholangiocarcinoma is not required

Learn more about our Research Philosophy

Key Dates

Letter of Intent Deadline:
Friday, July 16, 2021 @ 11:59 pm (EDT)

Applicants Notified of Decision Status of Letter of Intent:
Friday, August 27, 2021

Full Application Deadline:
(for those invited to apply based on the Letter of Intent)
Friday, October 8, 2021 @ 11:59 pm (EDT)

Notification of Award
Friday, December 14, 2021

Award Period:
April 1, 2022-March 31, 2023

Research Focus

  • Basic Science: Research using laboratory-based models without clinical data from patients
  • Translational Science: Research studying human samples or data obtained from human samples, annotated with clinical outcome data
  • Clinical Science: Studies of outcomes in human patients; includes population and epidemiology research


  • Doctor of Medicine
  • Doctor of Philosophy
  • Doctor of Pharmacy
  • Doctor of Veterinary Medicine

Academic Level

  • Postdoctoral Fellows and Clinical Fellows, within 3 years of terminal degree, who do not have faculty positions
  • Junior Faculty within first 4 years of appointment at the time of application; includes Instructors and Assistant Professors
  • There are no restrictions for applicants as to age or national origin

Institutional Requirements

  • Academic or medical or research institutions based anywhere worldwide
  • Sponsoring institution must assign a Mentor in the proposed research field who assumes responsibility and provides guidance for the research

Other Eligibility Requirements

  • Past Award recipients are not eligible to apply
  • Prior experience in the field of cholangiocarcinoma is not required


  • The number of grants in each funding cycle is determined based on the availability of funds. It is likely that CCF will award nine (9) new grants this year.
  • Each grant will provide up to $50,000 over one year for expenses related to the research project, which may include salary and benefits of the grant recipient.
  • CCF will not fund Indirect Costs

Key Components of a Letter of Intent

  • Translational research that has the ability to impact cholangiocarcinoma patient outcomes
  • Hypothesis-driven specific aims with well-designed analyses
  • Feasible project that is able to be completed within the 1-year time span of the grant
  • Identified Mentor who will be able to support the project aims and the applicant
  • Good statistical rigor

Evaluation of Letters of Intent

  • A limited number of applicants whose Letters of Intent are deemed most meritorious will be invited to submit full applications.
  • The Letters of Intent will be reviewed by the CCF Scientific Review Committee, comprised of established clinical, translational, and basic science researchers.
  • Applicants will be notified regarding LOI selection by Friday, August 27, 2021.

Letters of Intent (LOI) Narrative

  • The LOI should provide a brief summary of the proposed research project, including Significance, Investigator(s), Innovation, Approach, and Environment. (1 page limit)
  • The LOI must be accompanied by the applicant's Biographical Sketch.


Answers to our most frequently asked questions about the grant application process.