All Submitted Clinical Trials

Clinical Trials > All Submitted Clinical Trials

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Debio 1347-101 Phase I Trial in Advanced Solid Tumours With Fibroblast Growth Factor Receptor (FGFR) Alterations

Study Name Debio 1347-101 Phase I Trial in Advanced Solid Tumours With Fibroblast Growth Factor Receptor (FGFR) Alterations ClinicalTrials.gov Identifier (if applicable) NCT01948297 Clinical Trial Category (check all that apply) Beyond First Line Therapy Targeted Therapy Study Center Institution Name The University of Texas MD Anderson Cancer Center Institution Address 1515 Holcombe Blvd City Houston State Texas Zip Code 77030 Phone (713) 745-0746 Website http://www.mdanderson.org List additional Institutions (include address, phone number, and website) Dana-Farber Cancer Institute – Boston, Massachusetts, United States Massachusetts General Hospital – Boston, Massachusetts, United States Memorial Sloan-Kettering Hospital – New York, New York, United States Seoul National University Hospital – Seoul, Republic of Korea National Cancer Center Singapore – Singapore, Singapore Vall d’Hebron University Hospital – Barcelona, Spain Taipei... read more

AGSP 1217

A clinical trial to study AG-120 in previously treated patients with non-resectable or metastatic cholangiocarcinoma with an IDH1 mutation.

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INCT 1216

A Clinical trial to study the efficacy and safety of INCB054828 in patients with Advanced/Metastatic or surgically unresectable cholangiocarcinoma with FGFR2 translocations, other FGF/FGFR alterations or negative FGF/FGFR alterations who failed previous therapy.

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DeLiver-FGFR: A Pivotal Trial of ARQ 087 in Subjects with FGFR2 Gene Fusion Positive Inoperable or Advanced Intrahepatic Cholangiocarcinoma

FGFR2 genetic alterations (changes) are associated with different types of cancer. A drug that inhibits the activity of FGFR2 may be beneficial for the treatment of these cancers. In a recent trial, patients with intrahepatic cholangiocarcinoma with a genetic alteration known as “FGFR2 gene fusion”, benefited the most from treatment with ARQ 087.

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